Results 51 to 60 of about 448,630 (200)

Expanding the Phenotypic Spectrum of TXNDC15‐Related Ciliopathies to Include Joubert Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic loss‐of‐function variants in TXNDC15 are a known cause of the perinatally lethal ciliopathy Meckel syndrome (MKS). TXNDC15 encodes an endoplasmic reticulum (ER)‐resident thioredoxin‐domain protein required for ciliary transition zone integrity.
Zachary T. Sentell, Robert Geraghty, Juliana E. Arcila‐Galvis, Praveen Dhondurao‐Sudhindar, Sergio Foullerat Cañada, Fulvio D'Abrusco, Bosanka Jocic‐Jakubi, Miguel Barroso‐Gil, Valentina Serpieri, Thomas M. Kitzler, Kate E. Chandler, Eleanor G. Seaby, Gabrielle Wheway, Jennifer C. Dempsey, Dan Doherty, Enza M. Valente, John A. Sayer   +16 more
wiley   +1 more source

Catheter, surgical, or hybrid procedure: what future for atrial fibrillation ablation?

Journal of Cardiothoracic Surgery, 2021
Background The debate on the best treatment strategy for atrial fibrillation (AF) has expanded following the introduction of the so-called “hybrid procedure” that combines minimally invasive epicardial ablation with endocardial catheter ablation. However,
Giuseppe Nasso, Roberto Lorusso, Marco Moscarelli, Giuseppe De Martino, Angelo M. Dell’Aquila, Arash Motekallemi, Nicola Di Bari, Ignazio Condello, Pasquale Mastroroberto, Giuseppe Santarpino, Giuseppe Speziale   +10 more
doaj   +1 more source

A novel approach for Bachmann's bundle pacing implantation with the lumenless, catheter-delivered pacing lead

Europace
Background Bachmann's bundle pacing (BBp), which features a morphology similar to sinus rhythm (SR) and a shortened P-wave duration (PWD), was reported to significantly reduce the incidence and permanence of atrial fibrillation compared with the right ...
D. Yoshimoto, Y. Sakamoto, Y. Uemura, R. Yamaguchi, H. Naganawa, T. Suzuki   +5 more
semanticscholar   +1 more source

Comparative Analysis of Poly(Ethylene Glycol) (PEG) and Poly(2‐Ethyl‐2‐Oxazoline) (PEtOx) for Organic Solvent‐Free Lipid Nanoparticle Formulations

Angewandte Chemie International Edition, EarlyView.
Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber, Caroline T. Holick, Lucas Gath, Ekaterina Tsarenko, Vivien Bachmann, Stavroula Litsiou, Lukas Harder, Laura J. Rosenberger, Aleksandar Rusevski, Julian Kimmig, Stephan Culemann, Christian Franke, Claudia Waskow, Stephanie Hoeppener, Stephanie Schubert, Matthias Bros, Oliver Werz, Ivo Nischang, Michael Bauer, Adrian T. Press, Ulrich S. Schubert, Anja Traeger   +21 more
wiley   +1 more source

Histological description and bone compactness analysis of fossil (Aldabrachelys sp.) and extant Aldabra giant tortoise (Aldabrachelys gigantea) shell bone fragments

The Anatomical Record, EarlyView.
Abstract Aldabra Atoll, north of Madagascar and part of the Seychelles Outer Islands, is home to the Aldabra giant tortoise, Aldabrachelys gigantea, the only survivor of several species of giant tortoises that were once widespread on islands across the Western Indian Ocean.
Stefanie Herter, Nicole Klein, Massimo Delfino, Erik de Boer, Julian P. Hume, Jordan Bestwick, Frauke Fleischer‐Dogley, Annabelle Constance, Dennis M. Hansen, Torsten M. Scheyer   +9 more
wiley   +1 more source

Interatrial block as electrocardiographic predictive sign for atrial fibrillation in Internal Medicine Departments hospitalized patients

Italian Journal of Medicine, 2019
This study evaluated the correlation between interatrial block (IAB) and atrial fibrillation (AF) among patients admitted to our Internal Medicine Unit: 110 (group 1) were identified with electrocardiograms both in sinus rhythm and AF, and 123 (group 2 ...
Gianpaolo Bragagni, Chiu Hua Chen, Federico Lari, Gaetano Magenta   +3 more
doaj   +1 more source

Purification of Disassembled Capsid Protein by Hydroxyapatite Chromatography Enhances Virus‐Like Particle Recovery

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson, Nathaniel Parker, Shiyi Wang, Sara Daley, Aaron Cote, Michael A. Winters   +5 more
wiley   +1 more source

Substrate stiffness regulates cell fate and its applications in the repair of motor system: From two dimensions to three dimensions

BMEMat, EarlyView.
Substrate stiffness with different dimensions (2D and 3D) exerts a regulatory role in cellular behaviors, thereby governing cell fate decisions. Biomaterials with tunable stiffness exhibit substantial functional potential for the repair and regeneration of the motor system.
Zhiyuan Lu, Renwang Sheng, Ludvig J. Backman, Chuanquan Liu, Danning Zheng, Wei Zhang, Jialin Chen   +6 more
wiley   +1 more source

syha/mpas-bundle: mpas-bundle/v2.0.0

, 2023
<p>This mirrors the official release/2.0.0 from the public GitHub domain (https://github.com/JCSDA/mpas-bundle/tree/release/2.0.0), inheriting all licensing from the original version. It's designated for archiving in Zenodo, assigned its unique DOI,
Byoung-Joo (BJ) Jung, Mark J Olah, Junmei Ban, Dan Holdaway, Stephen Herbener, Benjamin Menetrier, Steve Vahl, Yannick Trémolet, Chris Snyder, Yonggang Yu, Maryam Abdi, Zhiquan (Jake) Liu, Jamie Bresch   +12 more
core   +1 more source

Conflicting Goals: Calorie Attentiveness and Consumer Food Bundle Choice

, 2021
Policymakers globally are interested in interventions that address the obesity epidemic. The restaurant industry, however, continues to promote less healthy, discounted food bundles.
Omebere-Iyari, O.
core   +3 more sources