Results 261 to 270 of about 1,625,523 (336)

Patient phenotyping for molecular profiling of neck and low back pain - Study protocol. [PDF]

Neurobiol Pain
Curatolo M, Payne C, Chiu AP, Tran NT, Yap N, Hofstetter CP, Lesnak JB, Arendt-Tranholm A, Price TJ, Jarvik JG, Turner JA.   +10 more
europepmc   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Evaluation of water treadmill training, lunging and treadmill training in the rehabilitation of horses with back pain. [PDF]

BMC Vet Res
Geiger T, Lindenhahn L, Delarocque J, Geburek F.   +3 more
europepmc   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source

Facilitators and barriers to deferring imaging for acute low back pain: a qualitative study. [PDF]

BMC Prim Care
Robinson CA, Gosdin MM, Cipri CS, Fridman I, Weinberg G, Jerant A, Hudnut A, Fenton JJ.   +7 more
europepmc   +1 more source

A woman with back pain

JACEP Open
Andrew J. Park, Thomas K. Hagerman, Kaitlyn N. Richter, Ashley Pajela Vorhies, Christopher R. Clark   +4 more
openaire   +3 more sources

Gradient Solvent Replacement‐Mediated Formation of High‐Strength Hydrogel‐Forming Microneedle for Long‐Term Drug Delivery

Advanced Science, EarlyView.
A high‐strength pH‐responsive hydrogel‐forming microneedle integrates gradient solvent replacement to enhance the mechanical properties of the acrylonitrile‐acrylic acid copolymer network, ensuring robust transdermal penetration and long‐term drug release.
Hui Li, Fengzhen Meng, Chengwei Hu, Zhiyun Wu, Liuzhi Hao, Caijun Sun, Lijing Fang, Fan Pan, Shaoquan Bian, Huipeng Li, Mingjun Li, Bo Liu, Xiaoli Zhao   +12 more
wiley   +1 more source

A rare etiology of sudden onset severe back pain: spinal subarachnoid hemorrhage. [PDF]

World J Emerg Med
Jin S, Huang Q, Wang R.
europepmc   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source

Global burden of low back pain attributable to smoking in 204 countries and territories in 1990-2021. [PDF]

Front Public Health
Wang B, Zhang J, Du P, Ke H, Zang L, Yuan S.   +5 more
europepmc   +1 more source