Results 301 to 310 of about 4,743,438 (408)

Synergistic Modulating of Mitochondrial Transfer and Immune Microenvironment to Attenuate Discogenic Pain

open access: yesAdvanced Science, EarlyView.
Gallic acid (GA) and copper ions self‐assemble to form nanoparticles, which are then modified with mitochondrial targeting peptides and gap junction modulator. These nanoparticles scavenge mitochondrial reactive oxygen species to induce M2 polarization and enhance intercellular mitochondrial transfer.
Xinzhou Wang   +13 more
wiley   +1 more source

Graded activity for chronic low back pain. [PDF]

open access: yesCochrane Database Syst Rev
Almeida de Oliveira L   +7 more
europepmc   +1 more source

Long-Term Improvements in Chronic Axial Low Back Pain Patients Without Previous Spinal Surgery: A Cohort Analysis of 10-kHz High-Frequency Spinal Cord Stimulation over 36 Months

open access: yesPain medicine (Malden, Mass.), 2018
A. Al-Kaisy   +8 more
semanticscholar   +1 more source

Pia Mater‐Penetrable Lipopolymer Nanoparticles for Gliocyte‐Targeted IL‐10 mRNA Therapy Alleviate Paclitaxel‐Induced Peripheral Neuropathy

open access: yesAdvanced Science, EarlyView.
The P6CIT lipopolymer demonstrates superior transfection efficacy in the spinal cord and DRG, as well as enhanced penetration of the pia mater compared to the MC3 ionizable lipid. Intrathecal delivery of P6CIT LPNPs enables effective transfection in the gliocytes in the spinal cord and DRG.
Xinrou Lin   +10 more
wiley   +1 more source

Biopsychosocial Strategies for Alleviating Low Back Pain in Late Mothers: A Systematic Review. [PDF]

open access: yesHealthcare (Basel)
Bulathwatta DT   +6 more
europepmc   +1 more source

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

open access: yesAdvanced Science, EarlyView.
Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang   +22 more
wiley   +1 more source

Low back pain and radicular pain : assessment and management [PDF]

open access: yes, 2017
Ailiet, Luc   +23 more
core   +1 more source

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