Results 311 to 320 of about 4,743,438 (408)

Gradient Solvent Replacement‐Mediated Formation of High‐Strength Hydrogel‐Forming Microneedle for Long‐Term Drug Delivery

Advanced Science, EarlyView.
A high‐strength pH‐responsive hydrogel‐forming microneedle integrates gradient solvent replacement to enhance the mechanical properties of the acrylonitrile‐acrylic acid copolymer network, ensuring robust transdermal penetration and long‐term drug release.
Hui Li, Fengzhen Meng, Chengwei Hu, Zhiyun Wu, Liuzhi Hao, Caijun Sun, Lijing Fang, Fan Pan, Shaoquan Bian, Huipeng Li, Mingjun Li, Bo Liu, Xiaoli Zhao   +12 more
wiley   +1 more source

Volume and Intensity of Walking and Risk of Chronic Low Back Pain.

JAMA Netw Open
Haddadj R, Nordstoga AL, Nilsen TIL, Skarpsno ES, Kongsvold A, Flaaten M, Schipperijn J, Bach K, Mork PJ.   +8 more
europepmc   +1 more source

A creative approach to the diagnosis and treatment of low back pain: case report and review of the literature. [PDF]

J Surg Case Rep
Finneran MM, Mittal A, Vyas A, Seibly J.
europepmc   +1 more source

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

Advanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang, Qi Zhang, Gang Lin, Ying Wang, Juan Li, Ping Wang, Jie Qi, Yuan Liang, Shiming He, Yanqing Gong, Ninghan Feng, Yang Wang, Yuanyuan Ma, Mei Zhang, Yue Shi, Xuesong Li, Weimin Ci, Liqun Zhou   +17 more
wiley   +1 more source

Motivation to exercise in patients with chronic low back pain. [PDF]

BMC Musculoskelet Disord
Nevelikova M, Zlamal F, Dosbaba F, Su JJ, Batalik L.   +4 more
europepmc   +1 more source

Effect of Radiofrequency Denervation on Pain Intensity Among Patients With Chronic Low Back Pain: The Mint Randomized Clinical Trials

Journal of the American Medical Association (JAMA), 2017
J. Juch, E. Maas, R. Ostelo, J. G. Groeneweg, J. Kallewaard, B. Koes, A. Verhagen, J. M. van Dongen, F. Huygen, M. V. van Tulder   +9 more
semanticscholar   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Lumbar Temperature Map of Elderly Individuals with Chronic Low Back Pain-An Infrared Thermographic Analysis. [PDF]

Diagnostics (Basel)
Albuquerque N, Gonçalves L, Strasse W, Gabriel J, Teixeira L, Cantista P.   +5 more
europepmc   +1 more source

A woman with back pain

JACEP Open
Andrew J. Park, Thomas K. Hagerman, Kaitlyn N. Richter, Ashley Pajela Vorhies, Christopher R. Clark   +4 more
openaire   +3 more sources