Results 31 to 40 of about 533,526 (309)
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat+8 more
wiley +1 more source
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen+4 more
wiley +1 more source
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald+74 more
wiley +1 more source
Prevalence of spinal pain in a population of Bosnia and Herzegovina
Objectives: To determine the prevalence and risk factors of spinal pain in the population of Bosnia and Herzegovina (BiH). Methods: This was a cross-sectional survey conducted online in November/December 2018. Participants were inhabitants of BiH of
Antonija Hrkać+3 more
doaj +1 more source
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski+13 more
wiley +1 more source
Why do so many patients opt for a surgical solution to lumbosacral (L-S) radicular pain? A rhetoric as well as specific question.Recently a Big Ten coach underwent the scalpel for the third time in two years. "Pain" not masochism was his response when questioned by the press, "Why the knife?"Most physicians and patients equate the severity of L-S ...
openaire +8 more sources
Pre‐Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case–Control Study
ABSTRACT Background Many patients with Multiple Sclerosis (MS) experience nonspecific symptoms prior to diagnosis. This period—the 'MS prodrome'—has been described in socio‐economically homogeneous cohorts to date. It remains unclear to what extent events prior to an MS diagnosis differ according to social determinants of health. Methods We conducted a
Pooja Tank+3 more
wiley +1 more source
Background Massage is suggested to be an effective treatment for chronic plantar heel pain (PHP). There is, however, no scientific evidence to support this claim.
Supamas Somphai+4 more
doaj +1 more source
Use of Numeric Rating Scale (NRS) as Visual Analogue Scale (VAS): Is this Clinically Significant?
Objective: To analyze statistically significant differences between the Numeric Rating Scale (NRS) and Visual Analogue Scale (VAS) in low back pain (LBP) patients. Study Design: Prospective longitudinal Study.
lbrahim Farooq Pasha+5 more
doaj +1 more source
Characteristics of Cerebral Palsy in the Midwestern US
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim+6 more
wiley +1 more source