Results 251 to 260 of about 53,399 (326)

Lifespan and Fecundity Impacts of Reduced Insulin Signalling Can Be Directed by Mito‐Nuclear Epistasis in Drosophila

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Insulin signalling extends lifespan across species but, in Drosophila, this effect can vary among populations. This variable response is underpinned by epistasis between mtDNA and nDNA. ABSTRACT The changing demography of human populations has motivated a search for interventions that promote healthy ageing, and especially for evolutionarily‐conserved ...
Rita Ibrahim   +4 more
wiley   +1 more source

Ozone-Tolerant Rice for Air-Polluted Environments. [PDF]

open access: yesGlob Chang Biol
Alam MS   +10 more
europepmc   +1 more source

Dysregulation of Rho‐Associated Coiled‐Coil Protein Kinase1 Depletes Neural Stem Cell Pool and Impairs Hippocampal Neurogenesis After Traumatic Brain Injury

open access: yesCell Proliferation, Volume 59, Issue 2, February 2026.
Following TBI, hippocampal neurogenesis in mice is impaired and affects cognitive function. This impairment is associated with the upregulation of p‐AKT/AKT mediated by ROCK1. ABSTRACT Traumatic brain injury (TBI) represents a global health burden, often resulting in persistent neurological deficits due to impaired hippocampal neurogenesis ...
Chaoqun Yao   +15 more
wiley   +1 more source

Frogs With a Southern Drawl: Wide Recognition Space Facilitates Heterospecific Aggression in Territorial Cricket Frogs

open access: yesEthology, Volume 132, Issue 2, Page 127-139, February 2026.
Northern cricket frogs (Acris crepitans) are sympatric throughout much of their range with their congener, Acris gryllus, and have overlapping call properties. We used field playback experiments to test to what extent A. crepitans males exhibit species recognition between these graded signals. Male A.
Julia L. Drennan, James P. Tumulty
wiley   +1 more source

PI3Kγ Deficiency Suppresses Cutaneous Squamous Cell Carcinoma Formation by Modulating the Tumour Microenvironment Rather Than by Directly Regulating Keratinocyte Proliferation

open access: yesExperimental Dermatology, Volume 35, Issue 2, February 2026.
ABSTRACT Phosphatidylinositol‐3 kinase (PI3K) is a central regulator of cell proliferation, survival, metabolism, and migration via the downstream AKT/mTOR pathway. Although activating mutations in the catalytic subunit of PI3Kα (p110α) have been documented in various cancers, including cutaneous squamous cell carcinoma (cSCC), the role of PI3Kγ (p110γ)
Aya Toyoshima   +10 more
wiley   +1 more source

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