Results 31 to 40 of about 15,234 (176)

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

Spontaneous Helical Alignment of Smooth Muscle Cells to Form a Medial Layer for Engineered Microvasculature

open access: yesAdvanced Healthcare Materials, EarlyView.
Spontaneous helical alignment of smooth muscle cells is induced within resistance‐vessel‐sized channels patterned within a hydrogel. The extent of the cells’ orientation angle is dependent on the presence and composition of ECM proteins lining the channel wall and cell seeding density.
Victoria D. Vest   +5 more
wiley   +1 more source

Integrated Assessment Methodology for Jack-Up Stability: Centrifuge Test of Entire Four-Legged Model for WTIVs

open access: yesApplied Sciences
Although wind turbine installation vessels (WTIVs) are increasingly operating in deepwater complex geological areas with larger scales, systematic research on and experimental validation of platform jack-up stability remain insufficient. This study aimed
Mingsheng Xiahou   +5 more
doaj   +1 more source

A case study of pyelolymphatic backflow demonstrated on CT

open access: yesRadiology Case Reports, 2022
Pyelolymphatic backflow is a rare type of pyelolymphatic fistula that occurs in cases of urinary obstruction. This phenomenon may help to decompress an acutely obstructed kidney, and therefore, alleviate renal function from deteriorating.
Vanessa Meihui Khoo, MBBS, BSc   +2 more
doaj   +1 more source

Overcoming Printing and Interfacial Challenges in Liquid Metal Direct Writing for Integrated Stretchable Electronics

open access: yesAdvanced Materials Technologies, EarlyView.
Liquid metal direct writing is advanced from a technological and fundamental point. Utilizing a kinematic bed, printing on large surfaces with irregularities is enabled. Furthermore, a pressure‐driven flow during printing is discovered that affects the thickness of traces.
Maximilian Krack   +15 more
wiley   +1 more source

Energy Characteristics of Full Tubular Pump Device with Different Backflow Clearances Based on Entropy Production

open access: yesApplied Sciences, 2021
In this study, the entropy theory was used as the evaluation standard of energy dissipation, and the effect of backflow clearance (the gap between motor rotor and motor shell) on energy characteristics of a full tubular pump was investigated by 3D ...
Fan Meng, Yanjun Li, Ji Pei
doaj   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

open access: yesAdvanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger   +9 more
wiley   +1 more source

Influence of Runner Downstream Structure on the Flow Field in the Draft Tube of a Small-Sized Water Turbine

open access: yesApplied Sciences
The flow in the draft tube of the water turbine is affected by the upstream flow and the inherent structure accompanied by various undesirable characteristics, affecting the efficient and stable operation of the water turbine. Changing the flow structure
Lingdi Tang   +4 more
doaj   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

open access: yesAdvanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong   +14 more
wiley   +1 more source

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