Results 101 to 110 of about 14,273,081 (281)
Gas Hydrates: It's a Gas [PDF]
In this activity, students will discover the importance of carbon, where carbon is stored on Earth, and that the largest reservoir of carbon is in the form of gas hydrates where methane and other hydrocarbon gases are trapped in a lattice of water ...
core +4 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Volcanoes, Plates, and Chains [PDF]
In this lesson students will discover how seamounts in the Axial-Cobb-Eikelberg-Patton chain were formed. They will learn about the processes that form seamounts, describe the movement of tectonic plates in the Gulf of Alaska region and explain the types
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Phosphorus and the Green Scum [PDF]
This resource explains the relationship between the overabundance of the element phosphorus in the environment and explosive algae growth (called algae blooms or green scum) as well as the progress toward eutrophication.
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Paleoclimatological Proxies: History's Thermometers [PDF]
In this lesson, students discover how deep-water corals can be used to determine long-term patterns of climate change. They will learn that these corals inhabit seamounts in the Gulf of Alaska and that oxygen contained in the calcium carbonate of their ...
core
Noises on—How the Brain Deals with Acoustic Noise
BiologyWhat is noise? When does a sound form part of the acoustic background and when might it come to our attention as part of the foreground? Our brain seems to filter out irrelevant sounds in a seemingly effortless process, but how this is achieved remains ...
Livia de Hoz, David McAlpine
doaj +1 more source