Results 111 to 120 of about 14,273,081 (281)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Alien Invasion: Invasive Species (title provided or enhanced by cataloger) [PDF]
Using the example of the Eastern United States continental shelf, this lesson helps students understand how alien species enter non-native habitats, what problems are associated with these species, and what can be done about them.
core
Research progress on time of ventilator circuit replacement
Huli yanjiu, 2016 It analyzed the background of the ventilator circuit replacement time,described relevant guidelines and implementation status at home and abroad.And it pointed out problems existed in present studies,so as to promote deep study of ventilator circuit ...
韩明星, 商临萍
doaj
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Charleston Bump Expedition: A Piece of Cake [PDF]
In this lesson students will investigate the ecology of benthic communities of the Charleston Bump, a series of rocky scarps, mounds, overhangs, and flat pavements that rise from the surface of the Blake Plateau in the Atlantic Ocean off Charleston ...
core
Mountains in the Sea: Fishy Deep-sea Designs [PDF]
In this activity, students will focus on adaptations of fishes living in the mesopelagic and bathypelagic zones of the deep ocean. The students will learn about the physical location of deep water habitats along the Hudson Shelf Valley and in Hudson ...
core +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Volcanism on the Pacific Ring of Fire: It's Going to Blow Up! (title provided or enhanced by cataloger) [PDF]
In this activity students familiarize themselves with some basic concepts of volcanology and investigate a portion of the Ring of Fire. They then research the answers to questions on the provided worksheet.
Mel Goodwin
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source