Results 41 to 50 of about 14,273,081 (281)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
In this activity, students will learn about the bathymetry of Hudson Canyon, a submarine canyon on the Atlantic coast of North America. As they study Hudson Canyon, they will compare and contrast topographic maps and bathymetric maps, investigate the ...
core +1 more source
Studia Rossica Posnaniensia, 2019 The article analyzes the correlation between the cognitive semantics of the words казаться, показаться and the ordinary/fictional narrative strategy, embodied in a context of a particular type.
Елена Чернцова
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Mountains in the Sea: Round and Round [PDF]
In this activity, students will explore circulation cells in the vicinity of seamounts. They will be able to interpret data from a three-dimensional array of current monitors to infer an overall pattern of water circulation, hypothesize what effect an ...
core +1 more source
Ontogenesis of the Architectural Periodical Press of the Soviet Era (1917–1931)
Управленческое консультирование, 2018 The article studies the development of the architectural periodicals of the Soviet period. Particular attention is accentuated on the chronological interval: 1917–1931.
I. I. Komarova, A. L. Tretyakov
doaj +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Integrable Background Geometries [PDF]
, 2014 This work has its origins in an attempt to describe systematically the integrable geometries and gauge theories in dimensions one to four related to twistor theory. In each such dimension, there is a nondegenerate integrable geometric structure, governed
Calderbank, David M. J.
core +4 more sources
The High Commissioner on National Minorities: Origins and Background [PDF]
Journal on Ethnopolitics and Minority Issues in Europe, 2013 The author discusses a few issues that explain the background for the proposal to create a HCNM and the obstacles it encountered before consensus could be achieved after lengthy and complicated negotiations at the CSCE Helsinki Follow-up Meeting in ...
Arie Bloed
doaj
Geology, Ecology, and Landscapes, 2021 This study establishes the local background and baseline values of elements in surface soils in Wassa area underlain by Birimian rocks using probability Q–Q plots. In this study, a total of 2868 soil samples were collected. The chemical elements in these
Raymond Kazapoe, Emmanuel Arhin
doaj +1 more source