Results 71 to 80 of about 14,273,081 (281)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
This lesson will help students understand what Gulf Stream rings are and why are they significant. Students will describe the overall flow of the Gulf Stream, explain how it affects biological communities in the North Atlantic Ocean, and describe Gulf ...
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Mountains in the Sea: Food Web Mystery [PDF]
In this activity, students will focus on some unique aspects of food webs in the vicinity of seamounts. They will be able to describe typical marine food webs, and explain why food is generally scarce in the deep-ocean environment. They will then discuss
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Mapping Seamounts in the Gulf of Alaska [PDF]
Students will investigate the physical description and mapping of seamounts in a Gulf of Alaska chain as they discover how seamounts in the Axial-Cobb-Eikelberg-Patton chain can be mapped to facilitate their exploration with a manned submersible.
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Steamship Portland: X-Storms [PDF]
In this lesson students will discover what causes extreme storms such as the Portland Gale of 1898 and the Halloween Nor'easter of 1991. They will identify and explain three factors that contributed to extreme storm conditions in the northwest Atlantic ...
Mel Goodwin
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
ADAPTIVE BACKGROUND DENGAN METODE GAUSSIAN MIXTURE MODELS UNTUK REAL-TIME TRACKING
Jurnal Informatika, 2008 Nowadays, motion tracking application is widely used for many purposes, such as detecting traffic jam and counting how many people enter a supermarket or a mall. A method to separate background and the tracked object is required for motion tracking.
Silvia Rostianingsih +2 more
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