Results 81 to 90 of about 5,205,464 (320)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Behaviour-based Knowledge Systems: An Epigenetic Path from Behaviour to Knowledge [PDF]

open access: yes, 2002
In this paper we expose the theoretical background underlying our current research. This consists in the development of behaviour-based knowledge systems, for closing the gaps between behaviour-based and knowledge-based systems, and also ...
Gershenson, Carlos
core   +2 more sources

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Investigating the Effect of Background Knowledge on Natural Questions [PDF]

open access: gold, 2021
Vidhisha Balachandran   +4 more
openalex   +1 more source

Interpreting and using CPDAGs with background knowledge

open access: yes, 2017
We develop terminology and methods for working with maximally oriented partially directed acyclic graphs (maximal PDAGs). Maximal PDAGs arise from imposing restrictions on a Markov equivalence class of directed acyclic graphs, or equivalently on its ...
Kalisch, Markus   +2 more
core  

Classical Forms in Modern Popular Music [PDF]

open access: yes, 2017
Popular music can be used as background knowledge by music educators in order to educate students on elements of classical music, such as form and compositional ...
Williams, Emily
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Knowledge in development aid and healthcare: a comparative analysis [PDF]

open access: yes, 2011
Effective delivery in the fields of development aid and healthcare relies on knowledge and its communication. Institutions, practitioners and the end-users are examined in these two fields as key actors in the production and communication of knowledge ...
Borda-Rodriguez, Alexander
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Incorporating Structured Commonsense Knowledge in Story Completion

open access: yes, 2018
The ability to select an appropriate story ending is the first step towards perfect narrative comprehension. Story ending prediction requires not only the explicit clues within the context, but also the implicit knowledge (such as commonsense) to ...
Chen, Jiaao, Chen, Jianshu, Yu, Zhou
core   +1 more source

Home - About - Disclaimer - Privacy