Results 91 to 100 of about 429,050 (291)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Morphological Background-Subtraction Modeling for Analyzing Traffic Flow

open access: yesModelling
Automatic surveillance systems have become essential tools for urban centers. These technologies enable intelligent monitoring that is both versatile and non-intrusive.
Erik-Josué Moreno-Mejía   +3 more
doaj   +1 more source

Local Compact Binary Count Based Nonparametric Background Modeling for Foreground Detection in Dynamic Scenes

open access: yesIEEE Access, 2019
Background subtraction is one of the most fundamental and challenging tasks in computer vision. Many background subtraction algorithms work well under the assumption that the backgrounds are static over short time periods but degrade dramatically in ...
Wei He   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The Dependence of Global Ocean Modeling on Background Diapycnal Mixing

open access: yesThe Scientific World Journal, 2014
The Argo-derived background diapycnal mixing (BDM) proposed by Deng et al. (in publish) is introduced to and applied in Hybrid Coordinate Ocean Model (HYCOM).
Zengan Deng
doaj   +1 more source

Background to the satisfaction chain: An investigation through structural equation modeling

open access: yesRevista Brasileira de Pesquisa em Turismo, 2013
Satisfaction studies have become crucial to improve the relationship between guests and hotels. With that in mind, this study analyzes the functional relations interfering in customer satisfaction in the hotel sector, based on the analysis of two ...
Wagner Junior Ladeira   +3 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

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