Results 51 to 60 of about 5,352,727 (302)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A GPU-Accelerated Modified Unsharp-Masking Method for High-Frequency Background- Noise Suppression

open access: yesIEEE Access, 2021
A digitized analog signal often encounters a high-frequency noisy background which degrades the signal-to-noise ratio (SNR) particularly in case of low signal strength.
Bhaskar Jyoti Borah, Chi-Kuang Sun
doaj   +1 more source

EXPRESS: Can location cues facilitate attentional suppression? [PDF]

open access: yes
The spatial cueing paradigm has illustrated that location cues result in attentional enhancement of target stimuli. However, evidence is mixed on whether proactive attentional suppression can be cued in a similar way. In this registered report, we used a
Poole, Daniel   +2 more
core   +1 more source

CARS-background suppression by phase-controlled nonlinear interferometry. [PDF]

open access: yes, 1990
We have developed a new technique for efficient suppression of the nonresonant background in coherent anti-Stokes Raman scattering (CARS). The advantage of this technique, which is based upon phase-controlled superposition of an appropriately selected ...
Lupke, G., Marowsky, G.
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Long-term virological suppression on first-line efavirenz + tenofovir + emtricitabine/lamivudine for HIV-1 [PDF]

open access: yes, 2019
OBJECTIVES: Evaluate long-term rates of virological failure and treatment interruption for people living with HIV (PLWHIV) with viral suppression on first-line efavirenz + tenofovir disoproxil fumarate + emtricitabine/lamivudine (EFV + TDF + FTC/3TC ...
Long-Term Virological Suppression Working Group, .
core   +1 more source

A Lightweight Small-UAV Detection via Synergistically Enhanced YOLOv11

open access: yesApplied Sciences
Detecting small unauthorized UAVs against complex backgrounds is challenging: targets can be just a few pixels wide, background clutter is pervasive, and the detection system must run on resource-constrained edge hardware.
Yucan Huang   +6 more
doaj   +1 more source

Suppression of background body signals in whole-body diffusion-weighted imaging for detection of bony metastases: a pilot study

open access: yesThe Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background Whole-body diffusion-weighted magnetic resonance is being developed as a tool for assessing tumor spread. Patients with known primary tumors require meticulous evaluation to assess metastasis for better staging; we attempted to detect bony ...
Heba Tollah Ahmed Ibrahim Eltonbary   +3 more
doaj   +1 more source

A modified topological derivative based background suppression for infrared dim small target detection

open access: yes, 2017
In the processing of infrared small target image which has low signal-To-noise ratio and complex background, the target detection and recognition are very hard.
Qin, Hanlin   +12 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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