Results 31 to 40 of about 8,522 (253)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Application of Radial Basis Functions Meshless Method for Solving an Inverse Parabolic Problem [PDF]

open access: yesMathematics and Modeling in Finance
In this paper, we propose an approximate solution to a one-dimensional inverse parabolic problem using radial basis functions (RBFs) and the Levenberg–Marquardt (LM) regularization method. This problem involves the backward heat equation.
Moslem Jamalpour Malekabadi   +2 more
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

STABILITY ESTIMATE FOR THE HEAT EQUATION BACKWARD IN TIME WITH NEUMANN AND INTEGRAL BOUNDARY CONDITIONS

open access: yesTạp chí Khoa học
In this paper, we first prove that the heat equation backward in time with Neumann and integral boundary conditions is an ill-posed problem. Then, we establish a stability estimate of Hölder type for this ill-posed problem.
Nguyen Van Duc
doaj   +1 more source

dynoGP: Deep Gaussian Processes for Dynamic System Identification

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This work introduces a novel class of deep models for system identification, dynamical deep Gaussian processes, which combine the strengths of data‐driven methods, such as those based on neural network architectures, with the ability to output a probability distribution for uncertainty representation.
Alessio Benavoli   +3 more
wiley   +1 more source

ILL-POSEDNESS AND STABILITY ESTIMATE FOR THE HEAT EQUATION BACKWARD IN TIME WITH DIRICHLET AND INTEGRAL BOUNDARY CONDITIONS

open access: yesTạp chí Khoa học
In this paper, we first prove that the heat equation backward in time with Dirichlet and integral boundary conditions is an ill- posed problem. Then, we establish a stability estimate of Hölder type for this ill-posed problem.
Nguyen Van Duc, Phan Hoai Linh
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

open access: yesAdvanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice   +2 more
wiley   +1 more source

Mixed convection in a channel with buoyancy force over backward and forward facing steps: The effects of inclination and geometry

open access: yesCase Studies in Thermal Engineering, 2021
This paper presents the computational results of heat transfer for a 2D laminar flow with different channel tilts with forward facing step and backward facing step, taking into account buoyancy forces for various bottom wall lengths.
Alibek Issakhov   +4 more
doaj   +1 more source

Influence of Scan Strategies in Electron Beam Powder Bed Fusion on Solidification, Microstructure, and High‐Temperature Compressive Properties of γ′‐Strengthened Inconel 738LC

open access: yesAdvanced Engineering Materials, EarlyView.
Experiments and thermophysical simulations were conducted to investigate the electron beam powder bed fusion electron beam (PBF‐EB/M) process for the γ′‐strengthened nickel‐based superalloy Inconel 738LC. The results demonstrate the impact of process‐induced microstructural variations on high‐temperature mechanical behavior, providing a basis for ...
Jan Niklas Petenati   +11 more
wiley   +1 more source

A Meshless Method Based on the Fundamental Solution and Radial Basis Function for Solving an Inverse Heat Conduction Problem

open access: yesAdvances in Mathematical Physics, 2015
We propose a new meshless method to solve a backward inverse heat conduction problem. The numerical scheme, based on the fundamental solution of the heat equation and radial basis functions (RBFs), is used to obtain a numerical solution.
Muhammad Arghand, Majid Amirfakhrian
doaj   +1 more source

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