Results 11 to 20 of about 256 (108)

Engineering Bacopa monnieri for improved bacoside content and its neurological evaluation [PDF]

Applied Microbiology and Biotechnology
Bacosides are triterpenoidal saponins with numerous pharmacological benefits. One of the significant drawbacks is the low availability of these bacosides.
Gajendra Singh Jeena, Sunil Kumar, Sachi Bharti, Neeti Singh, Ashutosh Joshi, Vaibhavi Lahane, Roshni Meghani, Akhilesh Kumar Yadav, Shubha Shukla, Vineeta Tripathi, Rakesh Kumar Shukla   +10 more
doaj   +2 more sources

Comparative Growth and Bacoside Production in Diploid and Tetraploid Bacopa monnieri (L.) Wettst. Cultivated Indoors via Hydroponic and Soil Culture Systems

Horticulturae
Bacopa monnieri, a cognitive-enhancing herb crucial in health supplements, faces quality variations and contamination by toxic substances in conventional field cultivation, which hinders industrial use.
Phithak Inthima, Kanyaratt Supaibulwatana   +1 more
doaj   +2 more sources

Repurposing Bacopa monnieri extracts containing Aquaporin-1 blockers to improve systemic oxidative stress: The BacOxy_I study

Advances in Redox Research
Summary: Objectives: To evaluate the efficacy of Bacopa monnieri (BM) containing Bacopaside II, a specific Aquaporin 1 (AQP1)-blocker, on systemic oxidative stress.
Hasnae Boughaleb, Roxane Verdoy, Amandine Pochet, Nathalie Fabian, Ramona Bella, Gopinath Muruganandam, Raphaël Frédérick, Karim Zouaoui Boudjeltia, Axelle Bourez, Cédric Delporte, Pierre Van Antwerpen, Annie Robert, Vincent Haufroid, Joseph P. Dewulf, Jean-Luc Balligand, Virginie Montiel   +15 more
doaj   +2 more sources

Beneficial effects of Bacopa monnieri extract on opioid induced toxicity

Heliyon, 2016
The present study examined the hepatotoxicity and nephrotoxicity of morphine and illicit street heroin and their amelioration by a standardized methanolic extract of Bacopa monnieri (L.) (mBME) in rats.
Muhammad Shahid, Fazal Subhan, Ihsan Ullah, Gowhar Ali, Javaid Alam, Rehmat Shah   +5 more
doaj   +2 more sources

Optimization of bacoside A3 content in hydroponically cultivated Bacopa monnieri

Journal of Horticultural Sciences
Bacopa monnieri L. is a popular ayurvedic plant known for its cognitive properties. The active principle in B. monnieri responsible for its brain-stimulating character is a group of saponins, specifically, bacoside A (bacoside A3, bacopaside II, and ...
Mrunal Saste, Vishal Warke, Gayatri Karri, Uday Annapure, Sunita Singh, Manish Raut, Vikas Randhe, Debjani Dasgupta, Girish Mahajan   +8 more
doaj   +3 more sources

Bioactive Constituents and Toxicological Evaluation of Selected Antidiabetic Medicinal Plants of Saudi Arabia

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
The purpose of this review is to summarize the available antidiabetic medicinal plants in the Kingdom of Saudi Arabia with its phytoconstituents and toxicological findings supporting by the latest literature. Required data about medicinal plants having antidiabetic activities and growing in the Kingdom of Saudi Arabia were searched/collected from the ...
Ali S. Alqahtani, Riaz Ullah, Abdelaaty A. Shahat, Rajadurai Murugan   +3 more
wiley   +1 more source

Perspectives on the Molecular Mediators of Oxidative Stress and Antioxidant Strategies in the Context of Neuroprotection and Neurolongevity: An Extensive Review

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
Molecules with at least one unpaired electron in their outermost shell are known as free radicals. Free radical molecules are produced either within our bodies or by external sources such as ozone, cigarette smoking, X‐rays, industrial chemicals, and air pollution.
Sheikh Shohag, Shomaya Akhter, Shahidul Islam, Tonmoy Sarker, Moinuddin Khan Sifat, Md. Mominur Rahman, Md. Rezaul Islam, Rohit Sharma, Gaurav Kumar   +8 more
wiley   +1 more source

Simultaneous Estimation of Scopoletin, Bacopaside-II, Bacopasaponin-C, Withanolide-A, and Withanoside-IV in a Clinically Proven Polyherbal Formulation for Treatment of Insomnia

Asian Journal of Complementary and Alternative Medicine, 2022
The present work is aimed to develop and validate a reverse phase high performance liquid chromatography (RP-HPLC) method for the simultaneous estimation of Scopoletin, Bacopaside-II, Bacopasaponin-C, Withanolide-A, and Withanoside-IV in a proprietary polyherbal formulation containing Bacopa monnieri (Brahmi), Convolvulus pluricaulis (Shankhapushpi ...
Sanman Kolhe, Sadanand Yewale, Pramod Kolsure, Shrikant Dhavale, Sriram Padmanabhan   +4 more
openaire   +1 more source

Taxonomic Distribution of Medicinal Plants for Alzheimer’s Disease: A Cue to Novel Drugs

International Journal of Alzheimer’s Disease, Volume 2020, Issue 1, 2020., 2020
Alzheimer’s disease (AD) is a neurodegenerative disorder manifested by decline in memory and mild cognitive impairment leading to dementia. Despite global occurrence of AD, the severity and hence onset of dementia vary among different regions, which was correlated with the customary use of medicinal herbs and exposure level to the causatives.
Muhammad Kamran, Rehana Kousar, Shakir Ullah, Siraj Khan, Muhammad Farooq Umer, Haroon Ur Rashid, Zakir Khan, Muhammad Ijaz Khan Khattak, Mujeeb Ur Rehman, Francesco Panza   +9 more
wiley   +1 more source

Despite Blocking Doxorubicin‐Induced Vascular Damage, Quercetin Ameliorates Its Antibreast Cancer Activity

Oxidative Medicine and Cellular Longevity, Volume 2020, Issue 1, 2020., 2020
Quercetin is a naturally occurring flavonol present in many foods. Doxorubicin is an effective anticancer agent despite its dose‐limiting cardiovascular toxicity. Herein, we investigated the potential protective effects of quercetin against doxorubicin‐induced vascular toxicity and its effect on the therapeutic cytotoxic profile of doxorubicin in ...
Hanan A. Henidi, Fahad A. Al-Abbasi, Mohamed A. El-Moselhy, Hany M. El-Bassossy, Ahmed M. Al-Abd, German Gil   +5 more
wiley   +1 more source