Results 121 to 130 of about 53,047 (298)

Venetoclax combined with cladribine, idarubicin, cytarabine (CLIA‐VEN) results in higher remission rates over conventional 7 + 3 chemotherapy without increased toxicity in newly diagnosed acute myeloid leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Summary Induction chemotherapy in fit de novo acute myeloid leukaemia (AML) patients has historically combined an anthracycline with standard‐dose cytarabine (‘7 + 3’) despite complete response (CR) rates of 50%–70%. In May 2023, our institution adopted the utilization of cladribine, cytarabine, idarubicin and venetoclax (CLIA‐VEN) for intensive ...
Benjamin J. Lee   +11 more
wiley   +1 more source

Prevention and management of febrile neutropenia in acute myeloid leukaemia and higher risk myelodysplastic syndrome: An international survey of current practice

open access: yesBritish Journal of Haematology, EarlyView.
Summary Febrile neutropenia causes substantial morbidity in acute myeloid leukaemia and higher risk myelodysplastic syndrome. We aimed to describe current practice and priorities for clinical trials in the prevention and management of febrile neutropenia across Australia/New Zealand (ANZ), the United Kingdom (UK), Canada and Europe.
Aleece MacPhail   +14 more
wiley   +1 more source

Point of care tests for hospital-acquired infections (HAIs) : economic analysis report [PDF]

open access: yes
A number of clinical/disease areas have been prioritised by the Technology Strategy Board (TSB) and Department of Health (DH) for the DIIA Innovation Platform.
Osipenko, Leeza, Szczepura, Ala
core  

Antibiotic use in equine dentistry: What is the evidence?

open access: yesEquine Veterinary Education, EarlyView.
Summary Antimicrobial resistance (AMR) poses a major threat to human and veterinary health. In equine dentistry, antibiotics are commonly used despite limited evidence supporting their efficacy. While antimicrobials include antifungals, antivirals, parasiticides and antiseptics, this review focuses specifically on antibiotics, aiming to inform ...
A. Sidwell, S. L. Hole, R. Pereira
wiley   +1 more source

Risk factors and outcomes of Stenotrophomonas maltophilia bacteraemia: a comparison with bacteraemia caused by Pseudomonas aeruginosa and Acinetobacter species.

open access: yesPLoS ONE, 2014
Stenotrophomonas maltophilia (SM) is an important nosocomial pathogen that exhibits intrinsic resistance to various antimicrobial agents. However, the risk factors for SM bacteraemia have not been sufficiently evaluated.
Go Hotta   +9 more
doaj   +1 more source

Patient safety in Europe: medication errors and hospital-acquired infections [PDF]

open access: yes, 2008
The Report was commissioned by the European Federation of Nurses Associations (EFN) in November 2007 in order to support its policy statements on Patient Safety (June 2004).
Burke, J.   +3 more
core   +1 more source

Possible association of short‐term complications and antimicrobial use in standing equine cheek tooth extractions 2018–2022

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Despite growing concerns about antimicrobial resistance, prophylactic antimicrobials continue to be routinely administered in many procedures, including dental extractions. Further evidence‐based research is needed on whether their use influences post‐operative complication rates.
Marlies Schnierer   +4 more
wiley   +1 more source

Meropenem‐Heparin Lock Therapy for Ochrobactrum intermedium Catheter‐Related Bloodstream Infection in a Pediatric Hemodialysis Patient: A Case Report and Literature Review

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background In pediatric hemodialysis patients with exhausted vascular access, managing rare pathogens like Ochrobactrum intermedium is challenging, often posing a dilemma between catheter removal and salvage attempts. There are few reports on the supported viability of meropenem‐heparin lock therapy for this purpose in pediatric patients. Case
Mônica Cristina Dutra Rodrigues   +4 more
wiley   +1 more source

Temporal trends in glycaemia and hospital outcomes in three metropolitan Australian hospitals, 2017–2024

open access: yesInternal Medicine Journal, EarlyView.
ABSTRACT Background Longitudinal data on in‐hospital glycaemia from Australian hospitals are limited. Aims: The aim of this study was to evaluate the efficacy and safety of current inpatient management strategies in New South Wales hospitals and to compare hospital‐acquired complication (HAC) rates in patients with and without diabetes.
Barbara Depczynski   +2 more
wiley   +1 more source

Antimicrobial Resistance and Infant Mortality in Sri Lanka: A Retrospective Cohort Study

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective Sepsis is a major cause of mortality among children, with the highest burden evident in neonates and young infants, particularly, in resource‐constrained healthcare settings. Despite this burden, there are insufficient published data to delineate the epidemiology of neonatal sepsis from many of these settings.
Gayana P. S. Gunaratna   +8 more
wiley   +1 more source

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