Results 171 to 180 of about 53,047 (298)

Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 396-421, February 2026.
Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen   +4 more
wiley   +1 more source

Action of Betulinic Acid in the Inhibition of Efflux Pump NorA in Staphylococcus aureus Strains: In Vitro and In Silico Approaches

open access: yesChemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT Antibiotic resistance poses a serious challenge to public health, particularly in the case of Staphylococcus aureus, a Gram‐positive bacterium that employs multiple resistance mechanisms, including efflux pumps such as NorA, which extrude antimicrobial compounds from the cell and reduce antibiotic efficacy. Therefore, the search for substances
Camila Aparecida Pereira da Silva   +10 more
wiley   +1 more source

Managing the Complex Intersection Between Substance Use Disorders and Infectious Diseases

open access: yes
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 3, March 2026.
Karissa Chow   +4 more
wiley   +1 more source

From Gut to Globe: Endogenous Endophthalmitis as a Sentinel Sign of Polymicrobial Intra‐Abdominal Infection

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT A 42‐year‐old male presented with 1 week of left eye redness, pain, and severe vision loss. Examination revealed anterior chamber fibrin, vitritis, and vitreous opacities. B‐scan ultrasonography showed mobile hyperechoic vitreous material with an attached retina.
Dhruv Sethi   +6 more
wiley   +1 more source

Bacteraemia due to E.coli in urinary tract infections in adults: a prospective epidemiological study following implementation of guidelines in a regional hospital. [PDF]

open access: yesBMC Infect Dis
Blancas-Altabella D   +8 more
europepmc   +1 more source

Non Pseudomonal Ecthyma Gangrenosum in an Immunocompetent Preterm Neonate: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Ecthyma gangrenosum (EG) is a rare but severe cutaneous infection, often caused by Gram‐negative organisms. It may indicate sepsis or underlying immunodeficiency, although cases in immunocompetent preterm infants are uncommon. We report the case of a preterm male neonate born at 34 + 5 weeks of gestation from a twin pregnancy, weighing 2030 g.
Abdessamad Lalaoui   +7 more
wiley   +1 more source

Meningococcal Serogroup Y Meningitis Reveals Inborn Factor B Deficiency

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
We report a novel case of complete complement Factor B deficiency revealed by invasive meningococcal disease. Using combined functional and genetic analyses, we demonstrate that loss of Factor B abolishes alternative pathway activity despite detectable protein levels. These findings provide a mechanistic framework relevant to complement diagnostics and
Camille Bougeard   +9 more
wiley   +1 more source

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