Results 51 to 60 of about 53,047 (298)

Temporal trends of enterococcal and vancomycin-resistant Enterococcus faecium bacteraemias in the northern Dutch-German cross-border region: a ten-year multicentre analysis

Journal of Global Antimicrobial Resistance
INTRODUCTION: Enterococcus species, particularly E. faecium and E. faecalis, are prominent causes of bacteraemia, posing significant clinical challenges due to antibiotic resistance.
Cansu Çimen, Andreas Voss, Joseph Hellkamp, Axel Hamprecht, Matthijs Berends   +4 more
doaj   +1 more source

Heparin bonded lines offer a solution that is difficult to implement Rapid Response to Dobson,R "Half the cases of bacteraemia in hospitals in England are linked to devices) [PDF]

, 2003
[Full text] The BMJ news report[1] that devices, particularly central venous lines, are linked to over half the cases of hospital acquired bacteraemia has long been a source of concern to clinicians in intensive care. Unfortunately, one simple, effective
Gilbert, R, Howard, R, Mok, Q
core  

High Prevalence of Non-Typhoid Salmonella Bacteraemia Among Febrile HIV Adult Patients Admitted at a Tertiary Hospital, North-Western Tanzania. [PDF]

, 2012
Bacterial blood stream infections constitute a significant public-health problem and it is an important cause of morbidity and mortality in HIV infected patients. Little is known in developing countries regarding salmonella bacteraemia among HIV patients.
Kabangila, Rodrick, Kataraihya, Johannes B, Kidenya, Benson R, Meremo, Alfred, Mshana, Stephen E, Peck, Robert   +5 more
core   +2 more sources

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Advanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li, Kang Wang, Wenzhuang Shi, Xu Wang, Duxin Li, Yanli Liu, Peng Zhang, Yipeng Wang   +7 more
wiley   +1 more source

An observational prospective study of topical acidified nitrite for killing methicillin-resistant Staphylococcus aureus (MRSA) in contaminated wounds [PDF]

, 2011
Background Endogenous nitric oxide (NO) kills bacteria and other organisms as part of the innate immune response. When nitrite is exposed to low pH, NO is generated and has been used as an NO delivery system to treat skin infections.
A Ghaffari, A Ghaffari, AD Ormerod, AD Ormerod, Amjad AJ Shah, Anthony D Ormerod, AP Johnson, C Miller, C Wendt, Carlo Leifert, CJ Yates, DJ Anderson, DL Monnet, F Jowkar, Gail P Ferguson, GW Dufresne, Hong Li, IM Gould, J Wilson, LR Martinez, M Barber, Nigel B Benjamin, R Goldman, R Phillips, R Phillips, R Weller, R Weller, R Weller, RS Dykhuizen, RS Dykhuizen, S Homer-Vanniasinkam   +30 more
core   +4 more sources

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Effect of the vancomycin minimum inhibitory concentration on clinical outcomes in patients with methicillin-susceptible Staphylococcus aureus bacteraemia: a systematic review and meta-analysis

BMJ Open, 2021
Objective The use of the vancomycin minimum inhibitory concentration (MIC) as a prognostic predictor in patients with methicillin-susceptible Staphylococcus aureus (MSSA) has been debated in the last decade.
Changcheng Shi, Jian Ye, Renjie Xu, Weizhong Jin, Shuang Xu, Fei Teng, Nengming Lin   +6 more
doaj   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, EarlyView.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

Yersinia enterocolitica in Italy. A case of septicemia and abdominal aortic aneurysm infection [PDF]

, 2018
We report a case of Yersinia enterocolitica septicemia in a 63-year-old patient admitted to the Vascular Surgery Department of Umberto I Hospital (Rome, Italy) for an abdominal aortic aneurysm.
Alessia Bressan, Cecilia Ambrosi, Cecilia Ambrosi, Daniela Scribano, Donatella M. Rodio, Francesco Speziale, Guido Antonelli, Maria Trancassini, Rita Tolli, Valeria Pietropaolo, Wassim Mansour   +10 more
core   +2 more sources