Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus. [PDF]
, 2019 Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection.
Jiang, Jiandong +8 more
core
Arthritis &Rheumatology, EarlyView.Objective The optimal treatment strategy for rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) remains uncertain, and direct comparative data between biologics are limited. This study aimed to evaluate the effectiveness and safety of abatacept compared with rituximab in patients with RA‐ILD.
Po‐Cheng Shih +3 more
wiley +1 more source
Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature
British Journal of Clinical Pharmacology, EarlyView.Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen +4 more
wiley +1 more source
Prevalence of Urinary Tract Infection, Bacteremia, and Meningitis Among Febrile Infants Aged 8 to 60 Days With SARS-CoV-2 [PDF]
, 2023 Paul L. Aronson +99 more
openalex +1 more source
Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]
, 2016 Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA +11 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe +9 more
wiley +1 more source
Clinical Outcomes With Definitive Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia With Retained Daptomycin and Ceftaroline Combination Therapy vs De-escalation to Monotherapy With Vancomycin, Daptomycin, or Ceftaroline [PDF]
, 2021 Courtney Nichols +3 more
openalex +1 more source
ESC Heart Failure, EarlyView.The study evaluated urinary chloride (uCl) and sodium (uNa) trajectories in 70 elderly patients hospitalized with acute heart failure and preserved ejection fraction (HFpEF). Urine samples were collected at baseline, 24, 48 and 72 h. A multiparametric approach assessed decongestion using the clinical congestion score (CCS), portal vein (PV) pulsatility
Jorge Campos +16 more
wiley +1 more source
Metabolic response to Klebsiella pneumoniae infection in an experimental rat model.
PLoS ONE, 2012 Bacteremia, the presence of viable bacteria in the blood stream, is often associated with several clinical conditions. Bacteremia can lead to multiple organ failure if managed incorrectly, which makes providing suitable nutritional support vital for ...
Fangcong Dong +5 more
doaj +1 more source
Preterm meconium‐stained amniotic fluid: A red flag for infection and adverse perinatal outcomes
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective Meconium‐stained amniotic fluid (MSAF) is uncommon in preterm deliveries and raises concerns about maternal and neonatal infectious risks. We aimed to evaluate maternal, perinatal, and microbiological outcomes in preterm deliveries complicated by MSAF compared to clear amniotic fluid (AF) and to assess outcomes in preterm versus term
Raneen Abu Shqara +3 more
wiley +1 more source