Results 41 to 50 of about 1,950,086 (247)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

In situ soil cementation with ureolytic bacteria by surface percolation

open access: yes, 2012
The possibility of using microbiological processes to improve the mechanical properties of soil by undisturbed in situ application has gained attention over recent years. This paper describes a new variation of in situ soil reinforcement technology based
Cheng, L.   +2 more
core   +1 more source

Evaluación de la bacteria Geobacter sp. en el tratamiento de agua residual del canal de Otavalo

open access: yes, 2019
Las aguas residuales de los camales o mataderos representan un grave problema ambiental debido a que están constituidas principalmente de altas cargas orgánicas que se liberan a ríos, provocando elevados niveles de contaminación en los mismos.
Cevallos Villacreses, Melany Alejandra
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Bacteria-genetic variant associations.

open access: yes, 2019
Bacteria-genetic variant associations.
Jacques Cosnes (81229)   +13 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Lactic acid bacteria as potential probiotics for the pharyngeal mucosa

open access: yes, 2011
The probiotic approach represents an alternative strategy in the prevention and treatment of infections in those body sites where the microbiota plays a role in the maintenance of physiological homeostasis.
M. Pesu   +9 more
core  

Rapid enumeration of bacteria grown on surimi-based products by flow cytometry

open access: yes, 2001
A rapid method to enumerate bacteria adhered on a surimi-based product (kamaboko) by flow cytometry (FCM) is described. To remove Escherichia coli cells from the surface of kamaboko, ultrasonic energy was used.
任, 恵峰   +11 more
core   +1 more source

Role of the cell-wall structure in the retention of bacteria by microfiltration membranes [PDF]

open access: yes, 2009
This experimental study investigates the retention of bacteria by porous membranes. The transfer of bacteria larger than the nominal pore size of microfiltration track-etched membranes has been studied for several kinds of bacterial strains.
Causserand, Christel   +3 more
core   +1 more source

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