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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Background Salmonella enterica Serovar Typhimurium (S. Typhimurium) is a major global foodborne pathogen. In our previous study, the S. Typhimurium ATCC 14028 strain harboring plasmid pHXY0908 survived at fourfold its ciprofloxacin MIC (MIC0908 = 0.125 ...
Mengyuan Li +10 more
doaj +1 more source
Pseudomonas cannabina pv. alisalensis (Pcal) causes bacterial blight on cabbage. In a previous study, we screened for reduced virulence using Tn5 transposon mutants and identified a LysR-type transcriptional regulator (LTTR) as a potential virulence ...
Kanon Yamamoto +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Citizens Monitoring Bacteria, 2005 [PDF]
This monthly report from the Iowa Department of Transportation is about the water quality management of Iowa's rivers, streams and ...
core
From the volcano effect to banding: a minimal model for bacterial behavioral transitions near chemoattractant sources [PDF]
Sharp chemoattractant (CA) gradient variations near food sources may give rise to dramatic behavioral changes of bacteria neighboring these sources. For instance, marine bacteria exhibiting run-reverse motility are known to form distinct bands around ...
Jashnsaz, Hossein +2 more
core +1 more source
“In-house” production of DNA size marker from a vaccinal Bacillus anthracis strain
Background and Objectives: DNA molecular weight marker is widely used in molecular biology experiments incurring considerable costs on low-budget settings.
Mohammad Sekhavati +6 more
doaj
Health care providers are an integral part of the era of mobile phones. During various activities linked to health care services, they come in contact with their cell phones regularly. These cell phones act as a perfect substrate for nosocomial pathogens,
Nguemaïm Ngoufo Flore +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Anti-bacterial activity of lysozyme in pitching yeast and effect of lysozyme on yeast fermentation [PDF]
Lysozyme has antibacterial activity against Gram-positive bacteria and has no activity against yeast. As such, lysozyme can be used for the specific inhibition of beer spoilage bacteria.
Van Landschoot, Anita
core

