Results 31 to 40 of about 3,660,719 (365)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Antimicrobial resistance profiles and molecular characterization of extended-spectrum β-lactamase/AmpC-harboring Klebsiella pneumoniae isolated from clinically ill dogs and cats in South Korea

BMC Veterinary Research
Background The emergence of ESBL/AmpC-producing K. pneumoniae is a significant concern in humans and veterinary medicine. This study aims to ascertain the antimicrobial resistance profiles and molecular characteristics of ESBL/AmpC-producing K ...
Yu-Jeong Hwang, Yeon-Hee Lee, Sekendar Ali, Bo-Youn Moon, Ji-Hyun Choi, Yeon-Kyeong Lee, Hee-Seung Kang, Ji-In Kim, Min Young Kim, Jae-Myung Kim, Suk-Kyung Lim   +10 more
doaj   +1 more source

An updated overview on the bacterial PhoP/PhoQ two-component signal transduction system

Frontiers in Cellular and Infection Microbiology
The PhoP response regulator and the cognate sensor kinase PhoQ form one of the two-component signal transduction systems that is highly conserved in bacteria. The PhoP/PhoQ system is a crucial mediator of signal transduction.
Meiqin Mao, Li He, Qingpi Yan
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Effects of Grazing in a Low Deciduous Forest on Rumen Microbiota and Volatile Fatty Acid Production in Lambs

Animals
The aim of the present study was to evaluate the effect of grazing the low deciduous forest (LDF) vegetation on the diversity of the rumen microbiome in growing lambs and its relationship with volatile fatty acid (VFA) profiles.
Raúl Ávila-Cervantes, Pedro González-Pech, Carlos Sandoval-Castro, Felipe Torres-Acosta, José Ramos-Zapata, Mónica Galicia-Jiménez, Ramón Pacheco-Arjona   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Discovery of the widespread site-specific single-stranded nuclease family Ssn

Nature Communications
Site-specific endonucleases that exclusively cut single-stranded DNA have hitherto never been described and constitute a barrier to the development of ssDNA-based technologies.
Martin Chenal, Alex Rivera-Millot, Luke B. Harrison, Ahmed S. Khairalla, Cecilia Nieves, Ève Bernet, Mansoore Esmaili, Manel Belkhir, Jonathan Perreault, Frédéric J. Veyrier   +9 more
doaj   +1 more source

Continuous watermelon cropping impairs plant growth by modifying soil biochemistry and rhizosphere microbial communities

Frontiers in Microbiology
Continuous watermelon cropping leads to increases in soil-borne diseases, which negatively affect plant growth. We investigated the impact of continuous watermelon cropping on soil biochemical properties, enzyme activities, microbial biomass, occurrence ...
HuiFang Lv, HuiFang Lv, Rui Sang, LingLing Huang, YueChen Long, DeCong Xu, MingXia Wang, QiAn Zhang, Li Jia, QiangQiang Ding, CongSheng Yan, HuanXin Zhang   +11 more
doaj   +1 more source

Comprehensive Evaluation of the MBT STAR-BL Module for Simultaneous Bacterial Identification and β-Lactamase-Mediated Resistance Detection in Gram-Negative Rods from Cultured Isolates and Positive Blood Cultures

Frontiers in Microbiology, 2018
Objective: This study evaluated the capability of a MALDI Biotyper system equipped with the newly introduced MBT STAR-BL module to simultaneously perform species identification and β-lactamase-mediated resistance detection in bacteremia -causing bacteria
Annie W. T. Lee, Johnson K. S. Lam, Ricky K. W. Lam, Wan H. Ng, Ella N. L. Lee, Vicky T. Y. Lee, Po P. Sze, Rahim Rajwani, Kitty S. C. Fung, Wing K. To, Rodney A. Lee, Dominic N. C. Tsang, Gilman K. H. Siu   +12 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source