Results 71 to 80 of about 2,032,795 (373)
Strength of bacterial adhesion on nanostructured surfaces quantified by substrate morphometry.
Nanoscale, 2019 Microbial adhesion and the subsequent formation of resilient biofilms at surfaces are decisively influenced by substrate properties, such as the topography.
Christian Spengler +10 more
semanticscholar +1 more source
Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli [PDF]
, 2011 To avoid detrimental interactions with intestinal microbes, the human epithelium is covered with a protective mucus layer that traps host defence molecules. Microbial properties such as adhesion to mucus further result in a unique mucosal microbiota with
Derde, Melanie +10 more
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Frontiers in PharmacologyIntroductionRespiratory tract infections (RTIs) contribute to pediatric morbidity and are often complicated by viral-bacterial superinfections, which exacerbate disease severity and increase antibiotic use.
Selvarani Vimalanathan +7 more
doaj +1 more source
The influence of surface chemistry on the kinetics and thermodynamics of bacterial adhesion
Scientific Reports, 2018 This work is concerned with investigating the effect of substrate hydrophobicity and zeta potential on the dynamics and kinetics of the initial stages of bacterial adhesion. For this purpose, bacterial pathogens Staphylococcus aureus and Escherichia coli
J. Oh +14 more
semanticscholar +1 more source
Biocompatibility and antibacterial properties of zirconium nitride coating on titanium abutments: An in vitro study [PDF]
, 2018 Improving soft tissue attachment and reducing bacterial colonization on titanium abutments are key factors for the long-term maintenance of healthy soft and hard peri-implant tissues.
Bressan, Eriberto +7 more
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Journal of Nanobiotechnology, 2020 Background Studying bacterial adhesion and early biofilm development is crucial for understanding the physiology of sessile bacteria and forms the basis for the development of novel antimicrobial biomaterials. Microfluidics technologies can be applied in
Hervé Straub +5 more
doaj +1 more source
Strategies in anti-adhesion therapy: A review article
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022 Bacterial diseases are an important cause of mortality and morbidity worldwide. The Improper and uncontrolled use of antibiotics contribute to the bacterial resistance to antibiotics. It is well known that the antibiotics stop bacterial infections by
Fitua Al-Saedi
doaj +1 more source
ACS Omega, 2018 Hospital-acquired infections can cause serious complications and are a severe problem because of the increased emergence of antibiotic-resistant bacteria.
Songmei Wu +5 more
semanticscholar +1 more source