Results 41 to 50 of about 985,537 (285)
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Comparative microbiome analysis of contracted breast capsules: a cross-sectional study
BMC MicrobiologyBackground Despite the implication of bacterial biofilms in the etiology of capsular contracture, there is limited research on the microbial structure of the contracted capsule.
Tae Hyun Park +7 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Production and Study of Antioxidant and Antibacterial Activities of Gelatin Nano-Capsules Containing Ferula assa-foetida Essential Oil [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2015 Background: Ferula assa-foetida is one of the common medicines that was used as antiseptic with a view to traditional uses, it can be used as a safe and effective drug to treat diseases particularly resistant bacterial infections.
Somayeh Jahani +4 more
doaj
Evaluation of the biocontrol activity of Frateuria defendens-derived metabolites against mollicutes
Plant Signaling & Behavior, 2022 Frateuria defendens is a candidate biocontrol agent that has been shown to reduce phytoplasma-related disease symptoms in grapevines and periwinkle plants. While a crude filtrate prepared from F.
Alaa Naama-Amar +3 more
doaj +1 more source
Антибиотики и Химиотерапия, 2021 One of the most used antimicrobial nitrofurans in Russian medical practice is nifuroxazide, which is distinguished by high therapeutic efficacy, drug safety, as well as economic availability in the treatment of acute bacterial diarrhea without ...
V. I. Kocherovets, S. G. Mardanly
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Sensitive Detection of Deliquescent Bacterial Capsules through Nanomechanical Analysis
, 2015 Encapsulated bacteria usually exhibit strong resistance to a wide range of sterilization methods, and are often virulent. Early detection of encapsulation can be crucial in microbial pathology.
Hayden K. Webb +3 more
core +1 more source