Results 91 to 100 of about 257,708 (271)

Hierarchical Targeting of TREM2+ Myeloid Cells via Acid‐Triggered OMVs Reprogram Immunosuppression and Suppress Osteolysis in Bone‐Metastatic TNBC

Advanced Science, EarlyView.
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen, Yucheng Xue, Xiao Ma, Liang Chen, Zhenxuan Shao, Hangxiang Sun, Haochen Mou, Fangqian Wang, Zilong Li, Yechao Shen, Zhaoming Ye, Xiaohua Yu, Shengdong Wang   +12 more
wiley   +1 more source

Caring for Cream on the Farm [PDF]

, 1923
Exact date of bulletin unknown.PDF pages ...
McKellip, Ivan
core  

Stress tolerance-related genetic traits of fish pathogen Flavobacterium psychrophilum in a mature biofilm [PDF]

, 2018
Indexación: Scopus.Flavobacterium psychrophilum is the causative agent of bacterial cold-water disease and rainbow trout fry syndrome, and hence this bacterium is placed among the most important salmonid pathogens in the freshwater aquaculture industry ...
Avendaño-Herrera, R., Levipan, H.A., Quezada, J.   +2 more
core   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Neutrophil Migration in the Activation of the Innate Immune Response to Different Flavobacterium psychrophilum Vaccines in Zebrafish (Danio rerio)

Journal of Immunology Research, 2015
Flavobacterium psychrophilum is a Gram-negative bacterium, responsible for the bacterial cold-water disease and the rainbow trout fry syndrome in freshwater salmonid fish. At present, there is only one commercial vaccine in Chile, made with two Chilean F.
Camila J. Solís, Matías Poblete-Morales, Sergio Cabral, Juan A. Valdés, Ariel E. Reyes, Ruben Avendaño-Herrera, Carmen G. Feijóo   +6 more
doaj   +1 more source

Comparative Microbial Dynamics in Crassostrea virginica and Crassostrea ariakensis [PDF]

, 2006
Considerations to introduce the Suminoe or Asian oyster Crassostrea ariakensis along the East Coast have raised many questions regarding ecology, economics, and human health.
Bean, Tanya J., Fowler, Patricia K., Morris, Jr., James A., Noble, Rachel T.   +3 more
core  

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Temperature-dependent shifts in gut microbiota and metabolome of olive flounder (Paralichthys olivaceus): implications for cold-water aquaculture expansion and probiotic applications

Animal Microbiome
Background In recent years, rising temperatures due to climate change have become significant stressors in aquatic environments, impacting disease incidence, growth, and gut microbiota in fish. Cold-water species, such as the olive flounder (Paralichthys
Che-Chun Chen, Yu-Ping Chen, Hsiao-Tsu Yang, Yu-Ling Chen, Chen-Wei Wu, Hong-Yi Gong, Yuan-Shing Ho, Ying-Ning Ho   +7 more
doaj   +1 more source

Methylation of foreign DNA overcomes the restriction barrier of Flavobacterium psychrophilum and allows efficient genetic manipulation

Applied and Environmental Microbiology
Flavobacterium psychrophilum causes bacterial cold-water disease (BCWD) in salmonids and other fish, resulting in substantial economic losses in aquaculture worldwide. The mechanisms F. psychrophilum uses to cause disease are poorly understood.
Seada Sloboda, Xinwei Ge, Daqing Jiang, Lin Su, Gregory D. Wiens, Carly A. Beveridge, Eric Duchaud, Mark J. McBride, Tatiana Rochat, Yongtao Zhu   +9 more
doaj   +1 more source

Aquaculture Asia, Vol. 11, No. 2, pp.1-38. April-June 2006 [PDF]

, 2006
Selection of high-health postlarvae: a prerequisite for sustainability of the Indian shrimp industry, by S. Saurabh, V. Kumar, S. Karanth and G. Venkateshwarlu. Nucleotides: novel immunostimulants in aquaculture feed, by P. Kalaimani Arasi, N. Felix.

core