Results 71 to 80 of about 7,887,836 (305)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
NMDS plot of total bacterial community composition in samples.
NMDS plot of total bacterial community composition in samples.
Linda A. Amaral-Zettler (206570) +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Climate-driven permafrost thaw and altered precipitation, combined with reliance on limited water sources and treatment infrastructure, challenge the microbiological safety of northern drinking water.
Marie-Ange Moisan +13 more
doaj +1 more source
Background Land use changes and related land management practices significantly alter soil physicochemical properties; however, their effects on the soil microbial community structure are still unclear.
Yoseph T. Delelegn +5 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Drivers of the composition of active rhizosphere bacterial communities in temperate grasslands [PDF]
Abstract The active bacterial rhizobiomes and root exudate profiles of phytometers of six plant species growing in central European temperate grassland communities were investigated in three regions located up to 700 km apart, across diverse edaphic conditions and along a strong land use gradient.
Selma Vieira +8 more
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
DIVERSITY OF CULTURABLE BACTERIAL COMMUNITY ASSOCIATED WITH THE CORAL Galaxea fascicularis FROM UJUNG KULON, INDONESIA [PDF]
Coral reefs are the most diverse marine ecosystems; however, little is known about their microbialdiversity in these ecosystems. The present study is aimed at investigating the general insights into the diversity of the bacterial community associated ...
Radjasa, Ocky Karna +3 more
core +1 more source
Assessment of Bacterial Community Assembly Patterns and Processes in Pig Manure Slurry. [PDF]
The bacterial community assembly patterns and processes are poorly understood in pig manure slurry. We collected pig manure slurry samples during the winter and summer seasons from eight commercial pig farms in South Korea.
Priyanka Kumari +2 more
doaj +1 more source

