Results 51 to 60 of about 754,218 (362)

Targeted Bacterial Immunity Buffers Phage Diversity [PDF]

Journal of Virology, 2011
ABSTRACTBacteria have evolved diverse defense mechanisms that allow them to fight viral attacks. One such mechanism, the clustered, regularly interspaced, short palindromic repeat (CRISPR) system, is an adaptive immune system consisting of genetic loci that can take up genetic material from invasive elements (viruses and plasmids) and later use them to
Härter, Jan Olaf Mirko, Trusina, Ala, Sneppen, Kim   +2 more
openaire   +3 more sources

Day-length is central to maintaining consistent seasonal diversity in marine bacterioplankton [PDF]

, 2010
Marine bacterial diversity is vast, but seasonal variation in diversity is poorly understood. Here we present the longest bacterial diversity time series consisting of monthly (72) samples from the western English Channel over a 6 year period (2003-2008)
Ben Temperton, Dawn Field, Ian Joint, Jack A. Gilbert, Paul Somerfield, Susan Huse   +5 more
core   +1 more source

Resolving environmental drivers of microbial community structure in Antarctic soils [PDF]

, 2009
Antarctic soils are extremely cold, dry, and oligotrophic, yet harbour surprisingly high bacterial diversity. The severity of environmental conditions has constrained the development of multi-trophic communities, and species richness and distribution is ...
Barrett, John E., Cary, S. Craig, Rejto, Lidia, Smith, Julie L., Tusnady, Gabor   +4 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A functional RNase P protein subunit of bacterial origin in some eukaryotes [PDF]

, 2011
RNase P catalyzes 5′-maturation of tRNAs. While bacterial RNase P comprises an RNA catalyst and a protein cofactor, the eukaryotic (nuclear) variant contains an RNA and up to ten proteins, all unrelated to the bacterial protein.
Bernal Bayard, Pilar, Gopalan, Venkat, Lai, Lien B., Lai, Stella M., Mohannath, Gireesha, Vioque Peña, Agustín   +5 more
core   +1 more source

Structural diversity of bacterial flagellar motors [PDF]

The EMBO Journal, 2011
The bacterial flagellum is one of nature's most amazing and well-studied nanomachines. Its cell-wall-anchored motor uses chemical energy to rotate a microns-long filament and propel the bacterium towards nutrients and away from toxins. While much is known about flagellar motors from certain model organisms, their diversity across the bacterial kingdom ...
Chen, Songye, Beeby, Morgan, Murphy, Gavin E., Leadbetter, Jared R., Hendrixson, David R., Briegel, Ariane, Li, Zhuo, Shi, Jian, Tocheva, Elitza I., Müller, Axel, Dobro, Megan J., Jensen, Grant J.   +11 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Exploring Bacterial Diversity: How Far Have We Reached?

Postępy Mikrobiologii, 2023
Many methods have been developed for studying and comparing bacterial diversity. These methods suffer from a number of drawbacks. Culture-dependent methods have a drawback that only a small number of bacteria can be cultured.
Pandey Himani, Lal Devi
doaj   +1 more source

100K Pathogen Genome Project. [PDF]

, 2017
The 100K Pathogen Genome Project is producing draft and closed genome sequences from diverse pathogens. This project expanded globally to include a snapshot of global bacterial genome diversity.
Weimer, Bart C
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source