Results 81 to 90 of about 754,218 (362)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

How Do Soil Bacterial Diversity and Community Composition Respond under Recommended and Conventional Nitrogen Fertilization Regimes?

Microorganisms, 2020
Shifts in soil bacterial diversity and community composition are suggested to be induced by elevated input of nitrogen (N) fertilization with implications for soil quality, and consequently production.
Sami Ullah, Ping He, Chao Ai, Shicheng Zhao, Wencheng Ding, Dali Song, Jiajia Zhang, Shaohui Huang, Tanveer Abbas, Wei Zhou   +9 more
doaj   +1 more source

The diversity of a distributed genome in bacterial populations

, 2010
The distributed genome hypothesis states that the set of genes in a population of bacteria is distributed over all individuals that belong to the specific taxon. It implies that certain genes can be gained and lost from generation to generation.
Baumdicker, F., Hess, W. R., Pfaffelhuber, P.   +2 more
core   +1 more source

A meta-analysis of the publicly available bacterial and archaeal sequence diversity in saline soils [PDF]

, 2013
An integrated view of bacterial and archaeal diversity in saline soil habitats is essential for understanding the biological and ecological processes and exploiting potential of microbial resources from such environments.
Gong, J (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Lab Environm Microbiol, Yantai, Peoples R China. jgong@yic.ac.cn, Gong, Jun, Ma, Bin   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Root, Nodule and Soil Bacterial Communities Associated With the Invasive Nitrogen‐Fixing Lupinus polyphyllus

Ecology and Evolution
Plants host microorganisms that can facilitate their success in becoming invasive. Established plant invasions might thus provide useful insights into potential changes in plant‐associated microbiomes over the course of the invasion process.
Satu Ramula, Seyed Abdollah Mousavi, Eero J. Vesterinen   +2 more
doaj   +1 more source

Assessment of the microbial communities associated with white syndrome and brown jelly syndrome in aquarium corals [PDF]

, 2013
Bacterial and ciliate assemblages associated with aquarium corals displaying white syndrome (WS) and brown jelly syndrome (BJS) were investigated. Healthy (n = 10) and diseased corals (WS n = 18; BJS n = 3) were analysed for 16S rRNA gene bacterial ...
Bythell, John C., Craggs, Jamie, Robson, James, Sweet, Michael J.   +3 more
core   +1 more source

Bioprospecting from marine sediments of New Brunswick, Canada : exploring the relationship between total bacterial diversity and actinobacteria diversity [PDF]

, 2014
Actinomycetes are an important resource for the discovery of natural products with therapeutic properties. Bioprospecting for actinomycetes typically proceeds without a priori knowledge of the bacterial diversity present in sampled habitats.
Duncan, Katherine, Gill, Krista A, Haltli, Bradley, Kerr, Russell G   +3 more
core   +2 more sources

Horizontal gene transfer and bacterial diversity

Journal of Biosciences, 2002
Bacterial genomes are extremely dynamic and mosaic in nature. A substantial amount of genetic information is inserted into or deleted from such genomes through the process of horizontal transfer. Through the introduction of novel physiological traits from distantly related organisms, horizontal gene transfer often causes drastic changes in the ...
Chitra, Dutta, Archana, Pan
openaire   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source