Results 251 to 260 of about 1,015,678 (312)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Effect of 5-fluorouracil on <i>Pseudomonas aeruginosa</i>: impact on virulence, biofilm formation, and bacterial growth. [PDF]

Front Microbiol
Niazy AA, Alrashed MM, Niazy AA.
europepmc   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

The effects of brines relevant to Mars and the ocean worlds on bacterial growth reflect salt-specific responses across water activity. [PDF]

Arch Microbiol
Zbeeb HZ, Joad MD, Zayed HH, Mahdi A, Chen F, Clark BC, Luhring TM, Schneegurt MA.   +7 more
europepmc   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

Advanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag, Janina A. Hoffmann, Tim Rogers, Christian A. Yates   +3 more
wiley   +1 more source

Bacterial Growth Temperature as a Horizontally Acquired Polygenic Trait. [PDF]

Genome Biol Evol
Farrell AA, Nesbø CL, Zhaxybayeva O.
europepmc   +1 more source

Pyramiding Recessive Resistance Genes Enhances Bacterial Leaf Spot Resistance in Peppers by Suppressing <i>In Planta</i> Bacterial Growth. [PDF]

Plants (Basel)
Poudel M, McDuffee S, Minsavage GV, Hutton SF, Sharma A, Jones JB.   +5 more
europepmc   +1 more source

Lovastatin and Resveratrol Synergistically Improve Wound Healing and Inhibit Bacterial Growth. [PDF]

Int J Mol Sci
AlJunaydil NA, Lambarte RNA, Sumague TS, Alghamdi OG, Niazy AA.   +4 more
europepmc   +1 more source

OpenLM: an open-source pixel super-resolution platform for lens-free microscopy with applications in bacterial growth monitoring and deep learning-based bacterial detection.

Lab Chip
Xu W, Ahmed S, Althumayri M, Tarman AY, Ulku MK, Yong K, Veli M, Ceylan Koydemir H.   +7 more
europepmc   +1 more source