Results 271 to 280 of about 1,520,593 (361)

MDM2-P53-V-ATPases axis driven by dehydroevodiamine to fight intracellular bacterial infection. [PDF]

Commun Biol
Wang H, He X, Wang L, Wang N, Niu X, Xu L, Kong L, Ma H, Wang Y, Deng X, Wang J.   +10 more
europepmc   +1 more source

Assessing the effect of different shapes of glyco-gold nanoparticles on bacterial adhesion and infections

, 2015
Preeti Chaudhary, Sivakoti Sangabathuni, Raghavendra Vasudeva Murthy, A. Martin Paul, Hirekodathakallu V. Thulasiram, Raghavendra Kikkeri   +5 more
openalex   +2 more sources

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

AI-Based D-Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug-Resistant Bacterial Infection. [PDF]

Adv Sci (Weinh)
Zhao Y, Kong Q, Gong H, Li L, Fu J, Wan B, Wang P, Li X, Wang Y, Zhang J, Yu Y, Yang X, Zuo X, Wang H, Li Y.   +14 more
europepmc   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Role of necroptosis in pulpitis: integration of bacterial infection, immune imbalance, and oxidative stress. [PDF]

PeerJ
Wang X, Wang Y, Pang Z, Gong P, Ma X, Qiu Y, Li J, Peng L, Liu Z.   +8 more
europepmc   +1 more source

Gynaecological bacterial infections: the physical and psychosocial consequences and challenges of management in resource-limited settings

, 2019
Charles Adiri, UI Nwagha, T C Okeke, Emmanuel Obiora Izuka   +3 more
openalex   +2 more sources

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Baseline Procalcitonin Levels and Their Association with Antibiotic Exposure and Clinical Outcomes in Critically Ill Patients with Suspected Bacterial Infection: A Retrospective Cohort Study. [PDF]

Healthcare (Basel)
Suranadi IW, Wisnawa ADF, Parami P, Hartawan IGAGU, Sinardja CD, Djedoma AI.   +5 more
europepmc   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source