Results 61 to 70 of about 140,542 (270)

Validation of multiplex PCR for the diagnosis of acute bacterial meningitis in culture negative cerebrospinal fluid

Arquivos de Neuro-Psiquiatria, 2019
This study evaluated the operational characteristics of the multiplex polymerase chain reaction (PCR) for cerebrospinal fluid (CSF) from patients with cellular and biochemical characteristics of acute bacterial meningitis and positive or negative CSF ...
Sérgio Monteiro de Almeida, Libera Maria Dalla Costa, Christian Siebra, Lavinia Nery Villa Stangler Arend, Keite da Silva Nogueira   +4 more
doaj   +1 more source

Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis

Journal of Translational Medicine, 2020
Background The timely diagnosis of bacterial meningitis is of utmost importance due to the need to institute antibiotic treatment as early as possible.
Leonardo Silva de Araujo, Kevin Pessler, Kurt-Wolfram Sühs, Natalia Novoselova, Frank Klawonn, Maike Kuhn, Volkhard Kaever, Kirsten Müller-Vahl, Corinna Trebst, Thomas Skripuletz, Martin Stangel, Frank Pessler   +11 more
doaj   +1 more source

Contribution of fibronectin-binding protein to pathogenesis of Streptococcus suis serotype 2 [PDF]

, 2002
In the present study we investigated the role of the fibronectin (FN)- and fibrinogen (FGN)-binding protein (FBPS) in the pathogenesis of Streptococcus suis serotype 2 in piglets. The complete gene encoding FBPS from S.
Greeff, A., de, Buys, H., Verhaar, R., Dijkstra, J., Alphen, L., van, Smit, H.E.   +5 more
core   +2 more sources

Chiari I Malformation: Review and Update of Current Treatment Options

Clinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo, Shuhei Shiino, Stephen Z. Shapiro, Brianna L. Hines, Noritaka Komune, Carmine Antonio Donofrio, Filippo Badaloni, Antonio Fioravanti, Joseph Lockwood, C. J. Bui, Aaron S. Dumont, R. Shane Tubbs   +11 more
wiley   +1 more source

Impact of pneumococcal conjugate vaccines on invasive pneumococcal disease-causing lineages among South African children

Nature Communications
Invasive pneumococcal disease (IPD) due to non-vaccine serotypes after the introduction of pneumococcal conjugate vaccines (PCV) remains a global concern.
Cebile Lekhuleni, Kedibone Ndlangisa, Rebecca A. Gladstone, Sopio Chochua, Benjamin J. Metcalf, Yuan Li, Jackie Kleynhans, Linda de Gouveia, Scott Hazelhurst, Ana D. S. Ferreira, Happy Skosana, Sibongile Walaza, Vanessa Quan, Susan Meiring, Paulina A. Hawkins, Lesley McGee, Stephen D. Bentley, Cheryl Cohen, Stephanie W. Lo, Anne von Gottberg, Mignon du Plessis   +20 more
doaj   +1 more source

Comparison of enterovirus detection in cerebrospinal fluid with Bacterial Meningitis Score in children

Einstein (São Paulo)
Objective To measure the role of enterovirus detection in cerebrospinal fluid compared with the Bacterial Meningitis Score in children with meningitis. Methods A retrospective cohort based on analysis of medical records of pediatric patients diagnosed
Frederico Ribeiro Pires, Andréia Christine Bonotto Farias Franco, Alfredo Elias Gilio, Eduardo Juan Troster   +3 more
doaj   +1 more source

FilmArray Meningitis/Encephalitis (ME) panel in the diagnosis of bacterial meningitis

Brazilian Journal of Infectious Diseases, 2019
The precise diagnosis of bacterial meningitis is essential. Cytological and biochemical examination of cerebrospinal fluid (CSF) are not specific.
Renan Barros Domingues, Márcio Vega dos Santos, Fernando Brunale Vilela de Moura Leite, Carlos Senne   +3 more
doaj   +1 more source

Association between genotypic diversity and biofilm production in group B Streptococcus [PDF]

, 2016
Background: Group B Streptococcus (GBS) is a leading cause of sepsis and meningitis and an important factor in premature and stillbirths. Biofilm production has been suggested to be important for GBS pathogenesis alongside many other elements ...
Davies, H. Dele, Gaddy, Jennifer A., Laut, Clare, Manning, Shannon D., Parker, Robert E., Zadoks, Ruth   +5 more
core   +2 more sources

AI + Drawing Enhances the Efficiency of Human Anatomy Education

Clinical Anatomy, EarlyView.
ABSTRACT Human anatomy is a fundamental core course in medical education, and its teaching effectiveness directly influences students' understanding and application of medical knowledge. However, traditional anatomy instruction often faces challenges such as limited teaching resources and the high cognitive difficulty students experience.
Fangfang Zhou, Yi Yang, Jiayou Liu, Xiaohua Zhu   +3 more
wiley   +1 more source

Sequelae due to bacterial meningitis among African children: a systematic literature review

BMC Medicine, 2009
Background African children have some of the highest rates of bacterial meningitis in the world. Bacterial meningitis in Africa is associated with high case fatality and frequent neuropsychological sequelae.
Moïsi Jennifer C, Steinhardt Laura C, Ulland Aaron J, Ramakrishnan Meenakshi, Were Fred, Levine Orin S   +5 more
doaj   +1 more source