Results 121 to 130 of about 3,626,493 (277)

Understanding antibiotic resistance via outer membrane permeability

Infection and Drug Resistance, 2018
Ishan Ghai,1,2 Shashank Ghai3 1School of Engineering and Life Sciences, Jacobs University, Bremen, Germany; 2Consultation Division, RSGBIOGEN, New Delhi, India; 3Leibniz University Hannover, Hannover, Germany Abstract: Collective antibiotic drug ...
Ghai I, Ghai S
doaj  

Two-Partner Secretion: Combining Efficiency and Simplicity in the Secretion of Large Proteins for Bacteria-Host and Bacteria-Bacteria Interactions

Frontiers in Cellular and Infection Microbiology, 2017
Initially identified in pathogenic Gram-negative bacteria, the two-partner secretion (TPS) pathway, also known as Type Vb secretion, mediates the translocation across the outer membrane of large effector proteins involved in interactions between these ...
Jeremy Guérin, Sarah Bigot, Robert Schneider, Susan K. Buchanan, Françoise Jacob-Dubuisson   +4 more
doaj   +1 more source

Dimeric structure of the bacterial extracellular foldase PrsA [PDF]

, 2015
Secretion of proteins into the membrane-cell wall space is essential for cell wall biosynthesis and pathogenicity in Gram-positive bacteria. Folding and maturation of many secreted proteins depend on a single extracellular foldase, the PrsA protein. PrsA
Schmidpeter, Philipp A. M., Hiller, Sebastian, Schmid, Franz X., Hunkeler, Moritz, Burmann, Björn M., Maier, Timm, Jakob, Roman P., Koch, Johanna R.   +7 more
core   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Molecular Machines that Facilitate Bacterial Outer Membrane Protein Biogenesis

Annual Review of Biochemistry
Almost all outer membrane proteins (OMPs) in Gram-negative bacteria contain a β-barrel domain that spans the outer membrane (OM). To reach the OM, OMPs must be translocated across the inner membrane by the Sec machinery, transported across the crowded periplasmic space through the assistance of molecular chaperones, and finally assembled (folded and ...
Matthew Thomas, Doyle, Harris D, Bernstein   +1 more
openaire   +2 more sources

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Import pathways of precursor proteins into mitochondria [PDF]

, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Pfaller, Rupert, Pfanner, Nikolaus, Steger, Heinrich F., Rassow, Joachim, Neupert, Walter   +4 more
core   +1 more source

A comprehensive approach to identification of surface-exposed, outer membrane-spanning proteins of Leptospira interrogans.

PLoS ONE, 2009
Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes belonging to the genus Leptospira. The leptospiral life cycle involves transmission via fresh water and colonization of the renal tubules of their reservoir hosts or
Marija Pinne, David A Haake
doaj   +1 more source

Transport of proteins across mitochondrial membranes [PDF]

, 1994
The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes
Neupert, Walter
core   +1 more source