Results 241 to 250 of about 3,626,493 (277)
Some of the next articles are maybe not open access.
Protein oligomerization in the bacterial outer membrane (Review)
Molecular Membrane Biology, 2009The formation of homo-oligomeric assemblies is a well-established characteristic of many soluble proteins and enzymes. Oligomerization has been shown to increase protein stability, allow allosteric cooperativity, shape reaction compartments and provide multivalent interaction sites in soluble proteins. In comparison, our understanding of the prevalence
Guoyu Meng +2 more
exaly +3 more sources
Export and assembly of bacterial outer membrane proteins
Antonie Van Leeuwenhoek, 1992Jan Tommassen +2 more
exaly +4 more sources
Protein import and export across the bacterial outer membrane
Current Opinion in Structural Biology, 2021The bacterial outer membrane forms an impermeable barrier to the environment, but a wide variety of substances must cross it without compromising the membrane. Perhaps, the most fascinating transport phenomenon is the import and export of very large protein toxins using relatively small β-barrel proteins residing in the outer membrane.
Jérémy, Guérin, Susan K, Buchanan
openaire +2 more sources
Assembly of Bacterial Outer Membrane Proteins
2012Various methods that are routinely used to study the subcellular localization of membrane proteins in wild-type Gram-negative bacteria fall short in genetic studies addressing the biogenesis of outer membrane proteins (OMPs). Here, we describe three biochemical methods that can be used in such studies to evaluate the proper assembly of OMPs into the ...
Grijpstra, J. +2 more
openaire +3 more sources
Modeling and simulation of bacterial outer membranes and interactions with membrane proteins
Current Opinion in Structural Biology, 2017The outer membrane (OM) of Gram-negative bacteria is composed of phospholipids in the periplasmic leaflet and lipopolysaccharides (LPS) in the external leaflet, along with β-barrel OM proteins (OMPs) and lipidated periplasmic lipoproteins. As a defensive barrier to toxic compounds, an LPS molecule has high antigenic diversity and unique combination of ...
Dhilon S Patel, Yifei Qi, Wonpil Im
openaire +2 more sources
Role of a Highly Conserved Bacterial Protein in Outer Membrane Protein Assembly
Science, 2003After transport across the cytoplasmic membrane, bacterial outer membrane proteins are assembled into the outer membrane. Meningococcal Omp85 is a highly conserved protein in Gram-negative bacteria, and its homolog Toc75 is a component of the chloroplast protein-import machinery.
Voulhoux, J.R. +4 more
openaire +3 more sources
Structural Aspects of Bacterial Outer Membrane Protein Assembly
2015The outer membrane of Gram-negative bacteria is predominantly populated by β-Barrel proteins and lipid anchored proteins that serve a variety of biological functions. The proper folding and assembly of these proteins is essential for bacterial viability and often plays a critical role in virulence and pathogenesis. The β-barrel assembly machinery (Bam)
Charles, Calmettes +2 more
openaire +2 more sources
Bacterial ß-Barrel Outer Membrane Proteins
2009ß-barrel outer membrane proteins constitute the second and less well-studied class of transmembrane proteins. They are present exclusively in the outer membrane of Gram-negative bacteria and presumably in the outer membrane of mitochondria and chloroplasts.
Pantelis G. Bagos, Stavros J. Hamodrakas
openaire +1 more source
Not all Bacterial Outer Membrane Proteins are β-Barrels
2023Abstract The discovery of WzA, an octomeric helical barrel integral bacterial outer membrane protein, has challenged the widely held understanding that all integral outer membrane proteins of gram-negative bacteria are closed β-barrels composed of transmembrane β-strands.
John Heido +5 more
openaire +1 more source