Results 101 to 110 of about 36,248 (243)
A Unified Framework for Biological Cognition: From Bacterial Chemotaxis to Human Metacognition [PDF]
Cognitive phenomena from bacterial chemotaxis to human metacognition appear disconnected across species, yet mounting evidence reveals underlying continuities that existing frameworks struggle to unify.
Tu, Mengyu
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Advanced Science, EarlyView.A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng +13 more
wiley +1 more source
CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction
Advanced Science, EarlyView.CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma +12 more
wiley +1 more source
Advanced Science, EarlyView.The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang +9 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun +19 more
wiley +1 more source
Bacterial peptidoglycan (murein) hydrolases
Most bacteria have multiple peptidoglycan hydrolases capable of cleaving covalent bonds in peptidoglycan sacculi or its fragments. An overview of the different classes of peptidoglycan hydrolases and their cleavage sites is provided.
Charlier P, Vollmer W, Joris B, Foster S
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Advanced Science, EarlyView.This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander +14 more
wiley +1 more source
, 2018 Plant pathology deals mainly with biotic phenomena that interfere with the normal metabolism of plants. Plants have developed mechanisms to deal with pathogenic attacks, while at the same time, pathogens are actively devising ways of overcoming the plant
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Trophic Diversity in Duckweed: Mixotrophy, More Than the Sum of its Extremes
Advanced Science, EarlyView.In the context of rising DOC in aquatic environments, mixotrophic duckweed may impact carbon cycling by acting as either a carbon sink, as they absorb CO2 through photosynthesis, or a carbon source, as they release CO2 through respiration of absorbed DOC, which depends on DOC concentration, light availability, temperature, and other environmental ...
Zuoliang Sun +5 more
wiley +1 more source
, 2008 Includes bibliographical references (leaves 104-115).Chalcopyrite is the most abundant primary copper sulphide mineral found worldwide. As copper grades of ores available for extraction decrease, heap bioleaching is gaining interest as a potential ...
Spurr, Nicholas Robert Louis
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