Results 221 to 230 of about 1,915,591 (341)

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Genetic Sequencing of a Bacterial Pneumonia Vaccine Produced in 1916. [PDF]

Vaccines (Basel)
Xiao Y, Gygli SM, Steen TY, Taubenberger JK.   +3 more
europepmc   +1 more source

Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia

Cell Death and Differentiation, 2017
Norberto González-Juarbe, K. Bradley, A. Shenoy, R. Gilley, L. Reyes, Cecilia A. Hinojosa, M. Restrepo, P. Dube, M. Bergman, C. Orihuela   +9 more
semanticscholar   +1 more source

Oral Health Care Services, Barriers and Enablers to Maintaining Good Oral Health in Motor Neurone Disease: A Scoping Review

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives The objective of this scoping review was to map existing literature on oral health and related care in individuals with Motor Neurone Disease (MND). Specifically, the review aimed to identify barriers and facilitators to maintaining oral hygiene, summarise available clinical guidelines and patient‐facing resources, and examine how ...
Mariam A. Khokhar, Lucy A. O'Malley, Anne‐Marie Glenny, Xiaohui Chen   +3 more
wiley   +1 more source

Differential regulatory mechanisms of gut-derived SCFAs (acetate, propionate, butyrate) on the pulmonary TLR2 signaling pathway and their roles in the inflammatory balance of bacterial pneumonia. [PDF]

Eur J Med Res
Chen H, Xu Y, Qiu J, Guan Z, Yu S, Ding Y.   +5 more
europepmc   +1 more source

Sustainable dyeing of silk with curled dock (Rumex crispus) extract for trace element removal, ultraviolet protection, antimicrobial and anti‐oxidant activity

Coloration Technology, EarlyView.
Abstract This study investigated the dyeability and functionality of silk dyed with curled dock leaf extract. The effects of sugar content and turbidity in the extracted dye solution on dyeing were analysed, along with K/S values and colour fastness, under varying temperatures and times.
Youngmi Park
wiley   +1 more source

Serum Interleukin-8 for Differentiating Invasive Pulmonary Aspergillosis from Bacterial Pneumonia in Patients with HBV-Associated Acute-on-Chronic Liver Failure. [PDF]

J Clin Transl Hepatol
Huang L, Feng Y, Wang W, Liu W, Liu Y, Chen L, Niu Y, Liu T, Song M, Xu Y, Yang Z, Chen G, Ning Q, Chen T, Zhu L.   +14 more
europepmc   +1 more source

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source

Impact of Antimicrobial-Resistant Bacterial Pneumonia on In-Hospital Mortality and Length of Hospital Stay: A Retrospective Cohort Study in Spain. [PDF]

Antibiotics (Basel)
Oterino-Moreira I, Pérez-Encinas M, Candel-González FJ, Lorenzo-Martínez S.   +3 more
europepmc   +1 more source

Bacterial Pneumonia in Patients with Cancer: Novel Risk Factors and Management.

Clinics in Chest Medicine, 2017
J. L. Wong, S. Evans
semanticscholar   +1 more source