Results 111 to 120 of about 68,312 (259)
Angína a colibacilos y sépticopiohemía a abscesos múltiples
Sesión del 24 de Octubre del 1934.
Adolfo Garra, Luis D. Bottaro
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
VIRUS Y BACTERIAS - FACULTAD DE CIENCIAS
Programa de Aprendizaje VIRUS Y BACTERIAS - FACULTAD DE ...
BIOLOGÍA
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
El síndrome metabólico (SM) es un conjunto de alteraciones metabólicas caracterizado principalmente por la presencia de obesidad abdominal, aumento de las concentraciones de triglicéridos, disminución de las concentraciones de HDL-colesterol ...
Abeijon Mukdsi, Maria Claudia +4 more
core
Evaluación microbiológica de pescados congelados producidos en Cumaná, Estado Sucre, Venezuela
El objetivo de este trabajo fue evaluar la frecuencia de bacterias y hongos, en muestras de ruedas de sierra (Scomberomorus spp) y merluza (Merluccius spp.) congeladas, producidas en Cumaná, estado Sucre, Venezuela.
Sara Centeno, Rossianny Rodríguez
doaj
Versatile vector tools for efficient protein screening across multiple expression systems
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Bacterias en paciente con tuberculosis
Dos imágenes de bacterias en un paciente con tuberculosis.Two pictures of bacteria in a patient with ...
Iglesias Rozas, José Rafael, 1942-
core
El objetivo de esta investigación fue la caracterización de la microflora halófila contaminante presente en muestras de pescado seco salado elaborado artesanalmente en el estado Sucre.
Crucita Graü +3 more
doaj
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

