Results 41 to 50 of about 68,312 (259)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Frontiers in MicrobiologyAquaculture has expanded rapidly over recent decades, positioning salmon farming as a major contributor to global food security while intensifying concern over antimicrobial use and the emergence of antimicrobial resistance (AMR).
Karla Camacho-Méndez +12 more
doaj +1 more source
Revista de Investigaciones Marinas, 2023 Se presenta una valoración del estado trófico de las aguas de la Zona Económica Exclusiva (ZEE) al sur de Cuba, a partir de indicadores microbiológicos y fitoplanctónicos.
Gladys Margarita Lugioyo +4 more
doaj
Identificación molecular de lactobacilos del tracto digestivo del lechón (Sus scrofa domesticus)
Manglar, 2016 Los animales cuando nacen no presentan bacterias en su tracto digestivo, este va adquiriendo múltiples bacterias de su entorno, las cuales se establecen y permanecen durante las diferentes etapas de su vida.
Héctor Sánchez, Gloria Ochoa
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Revista de Investigación Agraria y Ambiental, 2013 El mucílago y la pulpa de café, son subproductos semilíquidos involucrados en la generación de aguas residuales con alta concentración de materia orgánica y diversas especies de microorganismos, afectando negativamente la eficiencia de los tratamientos ...
Luis Felipe Orozco +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2023 Las bacterias compiten constantemente contra otros microorganismos principalmente por nutrientes en los diversos ambientes que habitan, es por ello que han desarrollado mecanismos que les confieren ventajas en su comunidad microbiana [1].
Luna-Pérez, Estephanie Elizabeth
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source