S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels +7 more
wiley +1 more source
Water is vital for life, and water void of bacterial contamination is vital for hospital consumption and use. This study aimed to determine the bacteriological quality and antibiogram of different water samples in some hospitals within Port Harcourt ...
Robinson, V. K. +4 more
doaj +1 more source
A chemo‐enzymatic colorimetric cascade for detecting ethylene glycol contamination
A chemo‐enzymatic cascade is developed for ethylene glycol (EG) detection. EG is oxidized by GoADH with C1‐mediated cofactor recycling to produce glycolaldehyde (GAL). GAL subsequently reacts with purpald to generate a detectable purple chromophore.
Tawatchai Singphongam +6 more
wiley +1 more source
Bacteriological quality and prevalence of foodborne bacteria in broiler meat sold at live bird markets at Mymensingh City in Bangladesh. [PDF]
Julqarnain SM +4 more
europepmc +1 more source
Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa +1 more
wiley +1 more source
Bacteriological Quality of Drinking Water and Hygienic Assessment of Water Cooler Dispensers in Higher Education Institution. [PDF]
Precha N +5 more
europepmc +1 more source
Constrictions and shear stress are key determinants of amyloidogenic light chain (AL) amyloidosis
In this study, we investigate how flow constrictions and shear stress trigger cardiac antibody light chain (AL) fibril formation and deposition. We mimic the mechanical forces exerted by the heart and the microvasculature network using a mini‐peristaltic pump setup and a grid‐type microchannel network, respectively.
Yuji Goto +11 more
wiley +1 more source
The Effect of Wet Coffee Processing Plant Effluent on Physicochemical and Bacteriological Quality of Receiving Rivers Used by Local Community: Case of Aroresa District, Sidama, Ethiopia. [PDF]
Amare G, Dobo B, Haile E.
europepmc +1 more source
ABSTRACT Atlantic cod farming experiences renewed growth in Norway, and increased awareness is essential to address emerging diseases in this species. There are few reports on gill diseases in cod, and to date, no viral gill infections of cod have been documented. In this study, we collected samples from three sequential time points in summer 2023 from
Mona C. Gjessing +4 more
wiley +1 more source
Bacteriological Quality and Public Health Risk of Ready-to-Eat Foods in Developing Countries: Systematic Review and Meta Analysis. [PDF]
Mengistu DA +3 more
europepmc +1 more source

