Results 111 to 120 of about 18,272 (219)

Eyes Toward the Clinic: Selective Inhibition and Degradation Approaches to Bromodomain‐Containing Proteins

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
The function of bromodomain‐containing proteins in regulating gene transcription is reviewed here, including the development of chemical probes and targeted protein degradation modalities (e.g., PROTACs). This extends to clinical efforts targeting the BET bromodomain‐containing proteins. Challenges of selectivity, future prospects, and the differential
Cole R. Scholtz, William C. K. Pomerantz
wiley   +1 more source

Barrier-to-autointegration factor protects against the cGAS-STING response to chromatin bridges. [PDF]

PLoS Genet
Chastant L, Normandin K, El-Mortada F, Servant MJ, Archambault V.   +4 more
europepmc   +1 more source

DAMP Laden Extracellular Vesicles From the Airways of Patients With Severe SARS-CoV-2 Respiratory Infection Compromise Inflammation and Cellular Metabolism. [PDF]

J Extracell Vesicles
Rees A, Richards O, Raikes ME, Chambers M, Reed SG, Battle C, Toghill H, Newey L, Joseph TJ, An H, Zhang H, Perry I, Webber J, Jones N, Thornton CA.   +14 more
europepmc   +1 more source

Insulin and Incretin Receptor Agonists Reciprocally Alter Their Blood-Brain Barrier Permeabilities. [PDF]

Int J Mol Sci
Fry A, Rose A, Weaver R, Hansen K, Blevins JE, Banks WA, Rhea EM.   +6 more
europepmc   +1 more source

MarkerMatch: a proximity-based probe-matching algorithm for joint analysis of copy-number variants from different genotyping arrays. [PDF]

Bioinformatics
Ivankovic F, Yu D, Shen J, Zhan L, Niarchou M, Kaylor A, Domènech L, Miller-Fleming TW, Porras LM, Giusti-Rodríguez P, Ophoff RA, Scharf JM, Mathews CA.   +12 more
europepmc   +1 more source

Diagnostic Criteria for Convergence Excess: Diagnostic Validity of Clinical Signs Associated with Near Esophoria. [PDF]

J Eye Mov Res
Cacho-Martínez P, Cantó-Cerdán M, Cervera-Sánchez Z, García-Muñoz Á.   +3 more
europepmc   +1 more source

Canonical BAF Complex [PDF]

, 2020
openaire   +1 more source

Cell fate specification during respiratory development requires ARID1A-containing canonical BAF complex activity. [PDF]

Nat Commun
Lee H, Jaquish A, Fernandes S, Zhao B, Elitz A, Cook K, Trovillion S, Bottasso-Arias N, Han SJY, Goodwin S, Russell NX, Saunders G, Zacharias AL, Brugmann SA, Whitsett JA, Sinner D, Sun X, Swarr DT, Zacharias WJ.   +18 more
europepmc   +1 more source

Medial cephalic to proximal ulnar artery fistulas enabled by a nitinol extravascular support device produce significantly higher maturation rates than brachial-based fistulas. [PDF]

J Vasc Surg Cases Innov Tech
Blessios G.
europepmc   +1 more source

Day-by-Day Ambient Determination of Nighttime Heterogeneous Oxidation of Particle-Phase Benzo[a]pyrene in an Urban Environment. [PDF]

Environ Sci Technol
Wang Q, Li Z, Huang Z, Zhu S, Li J, Qiao L, Zhou M, Huang D, Wang H, Fu Q, Yu H, Yu JZ.   +11 more
europepmc   +1 more source