Results 211 to 220 of about 35,041 (281)

GLP‐1R agonist semaglutide protects human forebrain organoids from cholesterol‐induced neurotoxicity

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Dysregulated cholesterol metabolism represents a critical metabolic stressor in the central nervous system, contributing to neuronal injury across multiple neurological conditions, including Alzheimer's disease (AD). While glucagon‐like peptide‐1 receptor (GLP‐1R) agonists show neuroprotective potential, their capacity to directly
Feifei Yu, Jiani Xu, Yibo Hou, Honghui Zheng, Lingyi Guo, Davit Khutsishvili, Cheng Hai, Wenxin Xu, Bailing Chen, Zitian Wang, Shaohua Ma   +10 more
wiley   +1 more source

Developmental Toxicity Study for the Antimalarial Drug Combination Cabamiquine‐Pyronaridine Using a Translational Approach

Birth Defects Research, Volume 118, Issue 10, October 2026.
ABSTRACT Background The safety of pharmacological treatments during pregnancy is a significant concern, as many medications lack comprehensive reproductive safety data. This creates gaps in therapeutic options for pregnant women, particularly malaria, which poses serious risks to maternal and fetal health.
Wookyung Kim, Geum‐Sil Cho, Andreas Gado, Tobias Hyun Ho Baeurle, Habib Karimi, Filippo Venezia, Claude Oeuvray, Thomas Spangenberg, Sebastian G. Wicha, Claudia Demarta‐Gatsi   +9 more
wiley   +1 more source

Surgical Management of Zollinger-Ellison Syndrome in Multiple Endocrine Neoplasia Type 1 an AFCE and GTE Cohort Study. (Association Francophone de Chirurgie Endocrinienne and Groupe d'étude des Tumeurs Endocrines). [PDF]

World J Surg
Gaujoux S, Pattou F, Cadiot G, Adham M, Bachellier P, Bail JP, Caiazzo R, Carrere N, Chaffanjon P, Deguelte S, Donatini G, Dousset B, Faron M, Gronnier C, Heyd B, Lifante JC, Lubrano J, Meurisse N, Mirallié E, Santucci N, Sauvanet A, Sebag F, Sulpice L, Thebault B, Tuech JJ, Walter T, Binquet C, Goudet P.   +27 more
europepmc   +1 more source

Minimizing Off‐Target Effects of CRISPR‐Cas9 With Optimized sgRNA: Evaluation of Efficiency and Specificity in the Tumor Protein 53 (TP53) Region

Biotechnology and Bioengineering, Volume 123, Issue 10, Page 2677-2689, October 2026.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) – Cas9‐based genome editing has emerged as a widely used tool across various disciplines, ranging from molecular biology to gene therapy. This revolutionary technology, which enables precise gene editing, represents a significant advancement in biotechnology, opening new frontiers for ...
Ali Mertcan Köse, Monia Ranalli, Drenka Trivanovic, Irina Maslovaric   +3 more
wiley   +1 more source

Does AI help humans make better decisions? A statistical evaluation framework for experimental and observational studies. [PDF]

Proc Natl Acad Sci U S A
Ben-Michael E, Greiner DJ, Huang M, Imai K, Jiang Z, Shin S.   +5 more
europepmc   +1 more source

Tomatidine Exposure During Early Myogenesis Promotes Hypertrophy of C2C12 Muscle Cells Through Increased Nuclei Accretion

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT During myogenesis or myofiber regeneration, a proliferating muscle cell must leave the cell cycle, commit to differentiate, and fuse to neighboring myoblasts to create multinucleated myotubes, and eventually mature myofibers. These stages can be manipulated by exogenous factors including signaling molecules, mechanical cues, and nutrient ...
Marissa K. Caldow, Kristy Swiderski, John H. V. Nguyen, Emily S. Haber, Kyla J. H. Fritz, Gordon S. Lynch   +5 more
wiley   +1 more source

Effect of a prior hypercapnia experience on recognition of hypercapnia in divers: a randomised controlled study. [PDF]

Diving Hyperb Med
Babbage T, van Waart H, Connell CJ, Gant N, Mitchell SJ, Vrijdag XC.   +5 more
europepmc   +1 more source

Fading Attention and the Pricing of Default Risk in the German Market for Structured Products

Journal of Futures Markets, Volume 46, Issue 10, Page 1787-1808, October 2026.
ABSTRACT Structured retail products are unsecured bonds subject to the default risk of the issuer. We analyze the price‐setting policy of issuers with respect to this default risk. Using a long‐term data set of discount certificates in the German market, we apply a time series IVX‐approach to find that (i) quoted prices do depend on issuer default risk,
Rainer Baule, Falk Jensen
wiley   +1 more source

Impact of Stepwise Balloon Angioplasty for De Novo Femoropopliteal Artery: A Retrospective Observational Study. [PDF]

Health Sci Rep
Tokuda T, Koshida R, Yoshioka N, Yamada T, Koyama A, Shimamura K, Nishikawa R, Oba Y, Hirano K.   +8 more
europepmc   +1 more source

An Investigation of the Relationship Between Central Bank Unconventional Monetary Policy and Bitcoin Activity

International Journal of Finance &Economics, Volume 31, Issue 4, Page 4970-4990, October 2026.
ABSTRACT This article investigates whether the unconventional monetary policy (UMP) measures pursued by the Federal Reserve, the Bank of England, the Bank of Japan, and the European Central Bank since the Global Financial Crisis (GFC) are associated with an appetite for cryptocurrency.
Niamh Wylie, Martha O'Hagan‐Luff
wiley   +1 more source