Results 191 to 200 of about 7,597 (257)

Developmental Toxicity Study for the Antimalarial Drug Combination Cabamiquine‐Pyronaridine Using a Translational Approach

open access: yesBirth Defects Research, Volume 118, Issue 10, October 2026.
ABSTRACT Background The safety of pharmacological treatments during pregnancy is a significant concern, as many medications lack comprehensive reproductive safety data. This creates gaps in therapeutic options for pregnant women, particularly malaria, which poses serious risks to maternal and fetal health.
Wookyung Kim   +9 more
wiley   +1 more source

Minimizing Off‐Target Effects of CRISPR‐Cas9 With Optimized sgRNA: Evaluation of Efficiency and Specificity in the Tumor Protein 53 (TP53) Region

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 10, Page 2677-2689, October 2026.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) – Cas9‐based genome editing has emerged as a widely used tool across various disciplines, ranging from molecular biology to gene therapy. This revolutionary technology, which enables precise gene editing, represents a significant advancement in biotechnology, opening new frontiers for ...
Ali Mertcan Köse   +3 more
wiley   +1 more source

Tomatidine Exposure During Early Myogenesis Promotes Hypertrophy of C2C12 Muscle Cells Through Increased Nuclei Accretion

open access: yesCell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT During myogenesis or myofiber regeneration, a proliferating muscle cell must leave the cell cycle, commit to differentiate, and fuse to neighboring myoblasts to create multinucleated myotubes, and eventually mature myofibers. These stages can be manipulated by exogenous factors including signaling molecules, mechanical cues, and nutrient ...
Marissa K. Caldow   +5 more
wiley   +1 more source

Fading Attention and the Pricing of Default Risk in the German Market for Structured Products

open access: yesJournal of Futures Markets, Volume 46, Issue 10, Page 1787-1808, October 2026.
ABSTRACT Structured retail products are unsecured bonds subject to the default risk of the issuer. We analyze the price‐setting policy of issuers with respect to this default risk. Using a long‐term data set of discount certificates in the German market, we apply a time series IVX‐approach to find that (i) quoted prices do depend on issuer default risk,
Rainer Baule, Falk Jensen
wiley   +1 more source

An Investigation of the Relationship Between Central Bank Unconventional Monetary Policy and Bitcoin Activity

open access: yesInternational Journal of Finance &Economics, Volume 31, Issue 4, Page 4970-4990, October 2026.
ABSTRACT This article investigates whether the unconventional monetary policy (UMP) measures pursued by the Federal Reserve, the Bank of England, the Bank of Japan, and the European Central Bank since the Global Financial Crisis (GFC) are associated with an appetite for cryptocurrency.
Niamh Wylie, Martha O'Hagan‐Luff
wiley   +1 more source

Navigating AI Convergence in Human–Artificial Intelligence Teams: A Signaling Theory Approach

open access: yesJournal of Organizational Behavior, Volume 47, Issue 8, Page 1338-1368, October 2026.
ABSTRACT Teams that combine human intelligence with artificial intelligence (AI) have become indispensable for solving complex tasks in various decision‐making contexts in modern organizations. However, the factors that contribute to AI convergence, where human team members align their decisions with those of their AI counterparts, still remain unclear.
Andria Smith   +3 more
wiley   +1 more source

Developing an at‐home dementia rehabilitation intervention: An iterative qualitative codesign study

open access: yesAustralian Occupational Therapy Journal, Volume 73, Issue 5, October 2026.
Abstract Introduction There is limited availability of community‐based rehabilitation for people with dementia. This study explored stakeholder perspectives to inform the design of an occupational therapy‐led at‐home dementia rehabilitation programme. Methods Four co‐design workshops were conducted over 6 months with 16 participants, including people ...
Clare Stephenson   +6 more
wiley   +1 more source

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