Results 31 to 40 of about 87,901 (242)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Robotically driven Error Augmentation training enhances post‐stroke arm motor recovery
Engineering ReportsStroke is a major cause of long‐term functional disability and requires physical rehabilitation. Due to population aging, the number of people post stroke is going to rise.
Eli Carmeli +6 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Field Studies Evaluating Bait Acceptance and Handling by Free-Roaming Dogs in Thailand
Veterinary Sciences, 2018 (1) Background: As part of the ongoing endeavor to eliminate dog-mediated human rabies in Thailand, renewed interest has been shown in oral vaccination of dogs as a supplementary tool to increase vaccination coverage of the dog population.
Suwicha Kasemsuwan +5 more
doaj +1 more source
Studia Quranika: Jurnal Studi Quran, 2023 In terms of discourse, it is known that hoaxes are one of the main problems in the creation of intolerance and acts of violence in the paradigm of religious people. In the Indonesian contest, it is realized that the problem of intolerance is based on an
Nurul Khair, Alfiyah Alfiyah
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Evaluation of food baits to capture Drosophila suzukii in the southern of Brazil
Anais da Academia Brasileira de Ciências, 2019 : Drosophila suzukii is one of the main pests of small fruits in the world. An effective monitoring is fundamental to detect the presence of the fly and to predict the infestation of fruits in new areas.
JUTIANE WOLLMANN +5 more
doaj +1 more source
Current Oncology, 2022 Background: Existing data on adding internal mammary nodal irradiation (IMNI) to the regional nodal fields are inconsistent. Methods: Randomized trials investigating the addition of IMNI to standard adjuvant radiation were identified. Hazard ratios (HRs)
Yasmin Korzets +5 more
doaj +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
Insān Ilahī as The Main Concept of Mulla Sadra’s Transcendental Human Existences
Nalar: Jurnal Peradaban dan Pemikiran Islam, 2020 This writing is library research on Mulla Sadra’s thought concerning the concept of insān ilahī as the main concept of transcendental existence discourse in response to western humanism paradigm because it consider vanishing the immaterial domain in ...
Nurul Khair +1 more
doaj +1 more source