Results 161 to 170 of about 292,971 (242)

A defence of Dworkin's arguments against Hartian legal positivism

open access: yes
Dworkin’s critique against the dominant Hartian position in general jurisprudence has no doubt been greatly influential ever since its appearance. Dworkin’s critique aims mainly at Hart’s separation thesis, namely the thesis that legal reasoning is ...
Chow, Zhen Yi
core  

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

A Framework for Thinking About the Potential Public Health Impact of Epidemiologic Research. [PDF]

open access: yesEpidemiology
Lesko CR   +5 more
europepmc   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Ad hominem arguments against parlamentarians

open access: yes
Denne oppgaven handler om bruk av personargumenter mot stortingspolitikere. Argumentasjonsteoretisk regnes personargumenter vanligvis som feilslutninger, fordi de forkaster en uttalelse på grunn av den som uttaler seg.
Ulvenes, Åsmund
core  

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

Informing robot design through early public engagement: lay perceptions of soft versus rigid socially assistive and rescue robots. [PDF]

open access: yesFront Robot AI
Fenn J   +9 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

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