Results 211 to 220 of about 292,971 (242)

Proportionality in Healthcare Governance: A Conceptual Review. [PDF]

Cureus
Papalexandris S, Fotiadis T, Seremeti L, Folinas D, Anastasiadou SD.   +4 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Creative and Critical Thinking and Modelling: Confluences and Implications for Science Teaching. [PDF]

J Intell
Gómiz-Aragón M, Aragón-Méndez MDM, Vieira RM, Tenreiro-Vieira C, Oliva JM.   +4 more
europepmc   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Five New Principles to Govern Intersex Pediatric Surgery: A Reply to Kevin G. Behrens. [PDF]

Linacre Q
Rehman R.
europepmc   +1 more source

Polygenic risk scores and embryonic screening: considerations for regulation. [PDF]

J Med Ethics
Haining CM, Savulescu J, Keogh L, Schaefer GO.   +3 more
europepmc   +1 more source

Human Stem Cell-Based Embryo Models in Implantation Research: Regulation, Consistency and Potential. [PDF]

Biomolecules
Holm S.
europepmc   +1 more source

War, ethics, and market presence: policy shifts of global pharmaceutical companies in Russia following the 2022 invasion of Ukraine. [PDF]

BMC Med Ethics
Hurst DJ, Darji K, Bobier CA.
europepmc   +1 more source

On the Limits of the Data Economy: The Case of Autonomous Vehicles. [PDF]

Sci Eng Ethics
Lundgren B.
europepmc   +1 more source