Results 101 to 110 of about 3,349,054 (303)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Sensory signals from the visual, vestibular, and proprioceptive systems are integrated based on their reliability to stabilize upright posture, in a process known as ‘sensory reweighting’. For example, when the sensory signals become noisy, the central nervous system decreases the reliance on such signals (down-weighting), while up-weighting ...
openaire +2 more sources
Fall 2013 Balance, Fairness, and Bias
, 2014 Recitation Guide - Fairness, Balance and Bias -- Fall 2013Recitation guide for the lesson Balance, Fairness, and Bias. Includes a 12 question quiz, lecture recap, assignments on balance, fairness, bias, news media bias, judging bias in news stories, and ...
Stony Brook University. School of Journalism. Center for News Literacy.
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Outcome of balance in dance movement training and unstable resistance training
, 2018 There will be an intervention with one group doing dance movement training and the other group unstable resistance training. We will assess the subjects through balance measurements before and after the intervention. In order to find out, if this type of
Nagy, Michelle Joy
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Analysis and comparison of competitive balance in the Spanish ACB basketball league : a preliminary study [PDF]
, 2009 Regardless its relevance in sports economics, competitive balance has not been studied neither in Spanish nor in European professional basketball. In this preliminary study we measured the competitive balance in the Spanish ACB League from seasons 1983 ...
Pino-Ortega, José +4 more
core +1 more source