Results 131 to 140 of about 7,696,607 (334)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
The Fragile Balance of Power and Leadership [PDF]
, 2016 The aim of this article is to first define effective leadership and power, highlighting the differences between the two. The focal point is that power and effective leadership are not interchangeable and should not be treated as such.
Jones, Angela M, York, Sheri L
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Scientific ReportsSpatial normalization of multisubject inner ear imaging data is challenging, due to both substantial intraindividual differences and the small size of the organ compared to other intracranial structures.
Johannes Gerb +5 more
doaj +1 more source
Targeting the Structural Balance [PDF]
This paper discusses whether a country should conduct fiscal policy by targeting a structural (or cyclically adjusted) fiscal balance. The paper is divided into three sections.
Laura dos Reis +2 more
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Research on Quasi-Elastic–Plastic Optimization of Reinforced Concrete Frame–Shear Wall Structures
BuildingsPrecise determination of structural elastic–plastic displacement and component states under rare earthquakes is crucial for structural design. This article proposes a quasi-elastic–plastic optimization method for reinforced concrete structures. First, an
Fengling Jin +4 more
doaj +1 more source