Results 131 to 140 of about 9,117,327 (386)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

In‐Stream Nitrogen Dynamics in a Point Source Influenced Headwater Stream During Baseflow Conditions

open access: yesWater Resources Research
Hydrochemical signatures are often traced back to their original sources using data collected at catchment outlets. However, this approach introduces uncertainties, as signals may add up, cancel each other out, or be subject to transformation processes ...
Caroline Spill   +2 more
doaj   +1 more source

Off-balance sheet exposures and banking crises in OECD countries [PDF]

open access: yes, 2012
Against the background of the acknowledged importance of off-balance-sheet exposures in the sub prime crisis, we seek to investigate whether this was a new phenomenon or common to earlier crises.
Barrell, R   +3 more
core  

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

In Balance With

open access: yesStudies in the Maternal, 2013
In Balance With (2012) is a live performance with Courtney Kessel and her daughter, Chloé, sitting at opposite ends of a seesaw. During the 30-minute performance, Kessel adds items representative of their lives to Chloé's side of the seesaw. After each group of items is added, she returns to her side to check the balance.
openaire   +3 more sources

Balanced and functionally balanced P-groups

open access: yesTopological Algebra and its Applications, 2018
Abstract In relation to Itzkowitz’s problem [5], we show that a c-bounded P-group is balanced if and only if it is functionally balanced.We prove that for an arbitrary P-group, being functionally balanced is equivalent to being strongly functionally balanced.
openaire   +5 more sources

Work and Family [PDF]

open access: yes, 1999
This survey offers in-depth analysis of workers' ability to balance work and family, the policies made available by employers to help their employees achieve this balance, and workers' attitudes about the policies designed to address the need to balance ...

core  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Sagittal balance of the spine

open access: yesEuropean spine journal, 2019
The static sagittal balance of the normal spine is a physiological alignment of the spine in the most efficient manner by the muscular forces. During gait, this balance is constantly thwarted by single-foot support.
J. Le Huec   +4 more
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

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