Results 141 to 150 of about 9,117,327 (386)

The Quest for Balance [PDF]

open access: yesCell Host & Microbe, 2015
Ancient healing traditions, particularly in the East, approach the human body holistically. We often hear about the balance between mind, body, and spirit. To modern-day scientists and clinicians embedded in empirical principles, the concepts of traditional Eastern medicine may seem unfounded, nebulous, or even false.
openaire   +3 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Safety of the HyperSound® Audio System in subjects with normal hearing

open access: yesAudiology Research, 2015
The objective of the study was to assess the safety of the HyperSound® Audio System (HSS), a novel audio system using ultrasound technology, in normal hearing subjects under normal use conditions; we considered preexposure and post-exposure test design ...
Ritvik P. Mehta   +3 more
doaj   +1 more source

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

open access: yesFrontiers in Immunology, 2014
As an essential component of innate immunity, macrophages have multiple functions in both inhibiting or promoting cell proliferation and tissue repair. Diversity and plasticity are hallmarks of macrophages.
Nan Wang, Hongwei Liang, Ke Zen
semanticscholar   +1 more source

A matter of balance

open access: yeseLife, 2018
New analyses shift the view that some forms of amyotrophic lateral sclerosis and frontotemporal dementia are due to defects in a single RNA-binding protein.
Aaron D Gitler, John D Fryer
openaire   +3 more sources

A business case for work-life balance in retail management. [PDF]

open access: yes, 2018
Retail is one of New Zealand’s largest sectors, employing close to 200,000 people full-time, but with changes in competition and growth in the industry, the expectations of retail managers are increasing, along with their workload. This research looks at
Brown, Caro, Taylor, Beverly
core  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

A precarious balance [PDF]

open access: yesCurrent Biology, 2004
Many areas of modern science and engineering owe their strength and vitality to a rich interplay of experiment, theory and computation. For example, quantum chemistry, aerodynamics, meteorology and membrane electrophysiology are all firmly based on extensive quantitative observations, sound theoretical formalisms and accurate, predictive calculations ...
openaire   +3 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

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