Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Tumor cell-intrinsic CD274/PD-L1: A novel metabolic balancing act with clinical potential [PDF]
, 2017 Curtis A. Clark +2 more
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Maternal and postnatal high-fat diet consumption programs energy balance and hypothalamic melanocortin signaling in nonhuman primate offspring [PDF]
, 2017 Elinor L. Sullivan +13 more
openalex +1 more source
An Improved Phase-Shifted DPWM Method for Reducing Switching Loss and Thermal Balancing in Cascaded H-Bridge Multilevel Inverter [PDF]
, 2020 Seok‐Min Kim +3 more
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
ORE1 balances leaf senescence against maintenance by antagonizing G2‐like‐mediated transcription
, 2013 Mamoona Rauf +8 more
openalex +2 more sources
Vertical Transmission of Listeria monocytogenes: Probing the Balance between Protection from Pathogens and Fetal Tolerance [PDF]
, 2018 Nicole Lamond, Nancy E. Freitag
openalex +1 more source
Vector coding reveals the underlying balance control strategies used by humans during translational perturbation [PDF]
, 2022 Naser Taleshi +4 more
openalex +1 more source
AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance.
Molecules and Cells, 2017 Daniel Garcia, R. Shaw
semanticscholar +1 more source