Results 231 to 240 of about 3,349,054 (303)

Factors Associated with Burnout Among Nurses: The Roles of Shift Work Characteristics, Work-Life Balance Satisfaction, and Chronic Disease. [PDF]

Healthcare (Basel)
Lotfy EM, Alenezi IN, Alanazi FK, Salem SGA, Ammar NAA, Saleh MSM, Alshmemri M, Aldughmi ON.   +7 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

The effects of video-based exergames on balance and agility in children with and without developmental coordination disorder: a meta-analysis. [PDF]

PeerJ
Zhao L, Wang J, Shang H, Liu P, Zhou J, Cheng Y.   +5 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Mass balance of the Greenland and Antarctic ice sheets from the 1970s to 2023. [PDF]

Sci Data
Otosaka IN, Shepherd A, Amory C, Horwath M, Ivins ER, King MD, Nowicki S, Payne AJ, Rignot E, Sørensen LS, Schlegel NJ, Simon KM, Smith BE, Sutterley TC, van den Broeke MR, Velicogna I, A G, Agosta C, Ditmar P, Döhne T, Engdahl ME, Fettweis X, Forsberg R, Gardner AS, Gilbert L, Goelzer H, Gourmelen N, Groh A, Hansen N, Harig C, Helm V, Khan SA, Kittel C, Langen PL, Larsen M, Loomis BD, McMillan M, Medley B, Melini D, Mottram RH, Muir A, Nilsson J, Noël B, Pattle ME, Roca I Aparici M, Sasgen I, Save HV, Scheuchl B, Schrama EJO, Schröder L, Seo KW, Simonsen SB, Slater T, Spada G, Vishwakarma BD, Wever N, Wiese DN, Wouters B.   +57 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Effects of exergaming on balance and functional performance in older adults with chronic conditions living in the community: a systematic review and meta-analysis. [PDF]

Front Public Health
Ge B, Luo J, Cheng X, Wang D, Liu R, Liao X.   +5 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source